Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771106 | 0.81 | GAA (0.47) | HSD17B10CYP3A4HTTMAPTALDH1A1 | |
| Trimethylammonium SCHEMBL11775950 | 0.77 | GAA (0.44) | CYP3A4HTTMAPTALDH1A1HPGD | |
| SCHEMBL21807618 | 0.75 | PKM (0.44) | TSHRHTTIDO1MAPTALDH1A1 | |
| SCHEMBL11773006 | 0.72 | GAA (0.40) | CYP3A4MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23709692 | 0.72 | ITGB2 (0.43) | ITGB2ICAM1ITGALHSD17B10TSHR | |
| SCHEMBL5044607 | 0.72 | ITGB2 (0.55) | ITGB2ICAM1ITGALHSD17B10TSHR | |
| SCHEMBL10834427 | 0.72 | ITGB2 (0.50) | ITGB2ICAM1ITGALHSD17B10TSHR | |
| SCHEMBL3165346 | 0.71 | ITGB2 (0.72) | ITGB2ICAM1ITGALHSD17B10TSHR | |
| SCHEMBL30472043 | 0.71 | FBP1 (0.58) | ITGB2ICAM1ITGALHSD17B10TSHR | |
| SCHEMBL224671 | 0.71 | FBP1 (0.58) | ITGB2ICAM1ITGALHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534440-B2 | Compounds with copper- or zinc-activated toxicity against microbial infection | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2026-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534440-B2 | Compounds with copper- or zinc-activated toxicity against microbial infection | TST, SLC39A11, SLC39A3 | ITGB2 4204/4885ICAM1 3831/4885ITGAL 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.