Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149158 | 0.83 | KIF11 (0.64) | KIF11ALDH1A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL27753815 | 0.79 | KIF11 (0.54) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL13455954 | 0.78 | KIF11 (0.46) | KIF11ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL27656873 | 0.76 | KIF11 (0.62) | KIF11ALDH1A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL23046586 | 0.75 | TAAR1 (0.43) | KIF11ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL20788831 | 0.75 | TAAR1 (0.54) | KIF11ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL6555564 | 0.74 | KIF11 (0.54) | KIF11ALDH1A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL7092683 | 0.74 | KIF11 (0.54) | KIF11ALDH1A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL10932721 | 0.74 | KIF11 (0.54) | KIF11ALDH1A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL913229 | 0.74 | KIF11 (0.54) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260029412-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER BY INHIBITING MITOCHONDRIAL STRESS-INDUCED PROTEIN CARBOXYL-TERMINAL ALANINE AND THREONINE TAILING (MSICAT-TAILING) | UNIV SOUTHERN METHODIST (US) | 2026-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260029412-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER BY INHIBITING MITOCHONDRIAL STRESS-INDUCED PROTEIN CARBOXYL-TERMINAL ALANINE AND THREONINE TAILING (MSICAT-TAILING) | AARS1, TUFM, HSPE1 | KIF11 1939/4885ALDH1A1 3395/4885HPGD 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.