Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32668768 | 1.00 | ALDH1A1 (0.39) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL32668708 | 0.86 | CA2 (0.40) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL32668915 | 0.86 | CA2 (0.40) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL8940310 | 0.83 | ALDH1A1 (0.35) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL8940478 | 0.82 | ALDH1A1 (0.38) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL32668938 | 0.81 | CA12 (0.36) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL27031968 | 0.81 | CA12 (0.36) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL27144937 | 0.81 | CA12 (0.36) | ALDH1A1GBA1C5AR1CYP24A1CA2 | |
| SCHEMBL5830519 | 0.81 | GBA1 (0.46) | ALDH1A1GBA1CYP24A1CA2CA9 | |
| SCHEMBL5245093 | 0.81 | GBA1 (0.46) | ALDH1A1GBA1CYP24A1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034106-A1 | Macrocyclic ligands for FK506-binding proteins for treatment of diseases with improved characteristics | UNIV DARMSTADT TECH (DE) | 2026-02-05 | — | — | US | disclosed |
| EP-4686495-A1 | MACROCYCLIC LIGANDS FOR FK506-BINDING PROTEINS FOR TREATMENT OF DISEASES WITH IMPROVED CHARACTERISTICS | Technische Universität Darmstadt (DE) | 2026-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034106-A1 | Macrocyclic ligands for FK506-binding proteins for treatment of diseases with improved characteristics | FKBP3, FKBP2, FKBP1B | ALDH1A1 4381/4885GBA1 3164/4885C5AR1 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.