Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31152185 | 0.81 | LMNA (0.51) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL31171486 | 0.81 | LMNA (0.51) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL31152335 | 0.80 | LMNA (0.53) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL29321909 | 0.79 | LMNA (0.41) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL31146891 | 0.74 | LMNA (0.49) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL31704122 | 0.73 | LMNA (0.51) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL21544137 | 0.73 | ALDH1A1 (0.46) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL31703883 | 0.73 | LMNA (0.51) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL28361998 | 0.72 | LMNA (0.57) | LMNAMAPTSLC6A4CYP1A2CYP2D6 | |
| SCHEMBL32669303 | 0.72 | LMNA (0.47) | LMNAMAPTSLC6A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | INCYTE CORP (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | LMNA 4176/4885MAPT 4877/4885SLC6A4 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.