Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.50 |
| ▸ | COMT | P21964 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669778 | 0.94 | FTO (0.47) | FTOCOMTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL32669969 | 0.88 | FTO (0.50) | FTOCOMTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30740965 | 0.84 | FTO (0.62) | FTOCOMTMEN1KMT2ALMNA | |
| SCHEMBL32669579 | 0.83 | FTO (0.49) | FTOCOMTMEN1KMT2AKDM4E | |
| SCHEMBL32669671 | 0.83 | FTO (0.46) | FTOCOMTMEN1KMT2ALMNA | |
| SCHEMBL32669610 | 0.83 | FTO (0.51) | FTOCOMTMEN1KMT2AKDM4E | |
| SCHEMBL32669968 | 0.82 | ALDH1A1 (0.36) | FTOCOMTMEN1KMT2AKDM4E | |
| SCHEMBL32669941 | 0.82 | FTO (0.45) | FTOCOMTMEN1KMT2AKDM4E | |
| SCHEMBL32669989 | 0.81 | SLC6A9 (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL32669868 | 0.80 | FTO (0.50) | FTOCOMTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | FTO 1/4885COMT 52/4885MEN1 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.