SCHEMBL32669869

SCHEMBL32669869

CN(CCOc1ccccc1)C(=O)/C(C#N)=C(\O)c1ccc(O)c(C#N)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.42
ESR1 P03372 6/20 0.40
SLC22A12 Q96S37 1/20 0.39
MMP2 P08253 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PARP10 Q53GL7 1/20 0.36
ESRRG P62508 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32670074 0.86 KMT2A (0.39) RAB9AESR1MMP2KMT2A
SCHEMBL32669930 0.85 RAB9A (0.38) RAB9AESR1SLC22A12MMP2MEN1
SCHEMBL32669648 0.84 KMT2A (0.51) RAB9AESR1MEN1KMT2A
SCHEMBL32670060 0.81 COMT (0.43) SLC22A12
SCHEMBL32669777 0.79 SLC22A12 (0.43) SLC22A12MEN1KMT2A
SCHEMBL30740965 0.78 FTO (0.62) RAB9AMEN1KMT2A
SCHEMBL32669597 0.78 ESR1 (0.38) RAB9AESR1KMT2A
SCHEMBL32669956 0.76 COMT (0.55) SLC22A12MEN1KMT2A
SCHEMBL32669921 0.75 SCN9A (0.45) RAB9AMEN1KMT2A
SCHEMBL32669611 0.75 ALDH1A1 (0.37) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 RAB9A 3162/4885ESR1 1076/4885SLC22A12 1753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.