Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263348 | 0.87 | TRPA1 (0.36) | TRPA1NPC1PKM | |
| SCHEMBL3266719 | 0.80 | KMT2A (0.35) | CNR2TP53 | |
| SCHEMBL3264313 | 0.71 | TRPA1 (0.36) | TRPA1NPC1PKM | |
| SCHEMBL1800384 | 0.70 | PDE5A (0.44) | CNR2CRHR1CRHR2LMNAPOLB | |
| SCHEMBL9960985 | 0.69 | NPC1 (0.36) | NPC1PKM | |
| SCHEMBL1801256 | 0.68 | CNR2 (0.43) | CNR2TRPA1TNKSTNKS2 | |
| SCHEMBL662588 | 0.68 | CTSA (0.40) | LMNANPC1POLB | |
| SCHEMBL4562114 | 0.67 | PORCN (0.44) | MAPT | |
| SCHEMBL667099 | 0.66 | CTSA (0.46) | LMNANPC1PKM | |
| SCHEMBL1799098 | 0.65 | CNR2 (0.42) | CNR2CRHR1CRHR2LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004390-A1 | QUINAZOLINE DIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-01-14 | — | — | WO | claimed |
| WO-2010004390-A1 | QUINAZOLINE DIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-01-14 | — | — | WO | disclosed |