SCHEMBL32670375

SCHEMBL32670375

COC(=O)c1ncc(N2CC(F)(F)C2)cn1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 1/20 0.39
▸ CYP4A11 Q02928 1/20 0.39
▸ CNR2 P34972 9/20 0.36
▸ SIK1 P57059 2/20 0.36
▸ SIK2 Q9H0K1 2/20 0.36
▸ SIK3 Q9Y2K2 2/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ KCNQ3 O43525 1/20 0.35
▸ KCNQ2 O43526 1/20 0.35
▸ MAPT P10636 1/20 0.34
▸ LRRK2 Q5S007 1/20 0.34
▸ NOTUM Q6P988 1/20 0.33
▸ HRH3 Q9Y5N1 1/20 0.33
▸ PIK3C3 Q8NEB9 1/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23960949 0.76 SIRT6 (0.46) NPC1RAB9AKMT2AMAPT
SCHEMBL23536740 0.75 CHRNB2 (0.48) NPC1RAB9AKMT2A
Hydrochloric Acid SCHEMBL25241141 0.74 CHRNB2 (0.47) NPC1RAB9AKMT2A
SCHEMBL14889617 0.73 SMO (0.41) CNR2MAPK1
SCHEMBL26115242 0.72 OPRK1 (0.40) NPC1RAB9AKMT2ALRRK2HRH3
SCHEMBL15709817 0.72 AOC3 (0.38) CNR2SIK1SIK2SIK3KMT2A
SCHEMBL31561318 0.70 PLK1 (0.36) SIK1SIK2SIK3NPC1RAB9A
SCHEMBL30535282 0.70 PLK1 (0.36) SIK1SIK2SIK3NPC1RAB9A
SCHEMBL10328696 0.70 CYP4F2 (0.44) CYP4F2CYP4A11NPC1RAB9AKMT2A
SCHEMBL30667961 0.70 RBP4 (0.36) CNR2KCNQ3KCNQ2NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) ELAVL1, ELAVL3, HNRNPL CYP4F2 2922/4885CYP4A11 2352/4885CNR2 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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