Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MARS1 | P56192 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933108 | 0.81 | AHR (0.67) | AHRSRD5A2HSD11B1ALDH1A1MARS1 | |
| SCHEMBL1725545 | 0.81 | HSD17B10 (0.56) | AHRSRD5A2HSD11B1ALDH1A1MARS1 | |
| SCHEMBL5544016 | 0.78 | AHR (0.57) | AHRSRD5A2HSD11B1ALDH1A1MARS1 | |
| SCHEMBL8759091 | 0.77 | CSNK2A1 (0.49) | HSD11B1ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL4214945 | 0.77 | ALDH1A1 (0.58) | AHRALDH1A1KDM4EMAPT | |
| SCHEMBL8757864 | 0.76 | CYP2A6 (0.58) | HSD11B1ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL11784870 | 0.74 | TDP1 (0.50) | AHRALDH1A1TP53KDM4EMAPT | |
| SCHEMBL7136627 | 0.74 | AHR (0.57) | AHRSRD5A2HSD11B1ALDH1A1MARS1 | |
| SCHEMBL1513663 | 0.74 | MEN1 (0.58) | AHRSRD5A2MARS1SMN1; SMN2MAPT | |
| SCHEMBL21723080 | 0.74 | AHR (0.57) | AHRSRD5A2HSD11B1ALDH1A1MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034094-A1 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | KOJIN THERAPEUTICS INC (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034094-A1 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | AIFM2, GPX4, HMOX1 | AHR 1566/4885SRD5A2 1046/4885HSD11B1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.