SCHEMBL3267069

SCHEMBL3267069

CC=C(O)C(=O)OCCCOc1ccc(CCC)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ALDH1A1 P00352 1/20 0.52
THRB P10828 1/20 0.47
PLA2G4B P0C869 1/20 0.46
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
PDE4A P27815 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
FFAR1 O14842 1/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 2/20 0.44
MEN1 O00255 2/20 0.44
S1PR4 O95977 1/20 0.44
S1PR1 P21453 1/20 0.44
S1PR3 Q99500 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3447968 0.91 FFAR1 (0.50) LMNAL3MBTL1FFAR1S1PR1S1PR3
SCHEMBL7078922 0.87 ALDH1A1 (0.55) LMNAL3MBTL1ALDH1A1THRBKDM4E
SCHEMBL7003272 0.83 POLB (0.60) LMNAL3MBTL1ALDH1A1THRBKDM4E
SCHEMBL27728967 0.82 HTT (0.59) LMNAL3MBTL1ALDH1A1THRBKDM4E
SCHEMBL7003273 0.82 ALDH1A1 (0.51) LMNAL3MBTL1ALDH1A1THRBKDM4E
SCHEMBL10946685 0.82 TDP1 (0.50) L3MBTL1ALDH1A1THRBSMN1; SMN2NPC1
SCHEMBL1263767 0.81 TDP1 (0.47) LMNAL3MBTL1ALDH1A1PLA2G4BCYP1A2
SCHEMBL3901525 0.80 THRB (0.66) LMNAL3MBTL1ALDH1A1THRBKDM4E
SCHEMBL8651592 0.80 FFAR1 (0.48) LMNAL3MBTL1ALDH1A1SMN1; SMN2FFAR1
SCHEMBL28626767 0.80 POLB (0.56) LMNAL3MBTL1ALDH1A1THRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1970043-A2 Method for fabricating endodontic, orthodontic and direct restorations having infused ceramic network Trustees of Boston University (US) 2008-09-17 EP claimed
US-6881488-B2 Method for fabricating endodontic, orthodontic, and direct restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 2005-04-19 US claimed
US-6271282-B1 Method for fabricating endodontic orthodontic and direct restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY 2001-08-07 US claimed
EP-1006095-A2 Method for fabricating endodontic, orthodontic, and direct restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 2000-06-07 EP claimed
US-5843348-A Method for fabricating odontoforms and dental restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 1998-12-01 US claimed
EP-0036272-B1 PERMANENT DENTAL RESTORATIVE COMPOSITIONS AND METHODS OF USING THEM ROHM AND HAAS COMPANY (US) 1985-01-09 EP claimed
EP-0036272-A2 Permanent dental restorative compositions and methods of using them ROHM AND HAAS COMPANY (US) 1981-09-23 EP claimed
CN-105143284-A Free-radical polymerization methods and articles thereby 3M INNOVATIVE PROPERTIES CO 2015-12-09 CN disclosed
CN-105051007-A High refractive index addition-fragmentation agents 3M INNOVATIVE PROPERTIES CO 2015-11-11 CN disclosed
CN-104870484-A ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO 2015-08-26 CN disclosed
CN-101048432-B Process for preparing crosslinkable oligomers NUPLEX RESINS BV 2013-09-11 CN disclosed
CN-103059204-A Method for producing crosslinkable oligomers NUPLEX RESINS BV 2013-04-24 CN disclosed
EP-0694298-B1 PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME SHOFU INC (JP) 2010-06-09 EP disclosed
US-5843348-A Method for fabricating odontoforms and dental restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 1998-12-01 US disclosed
US-5780525-A Photocurable composition for electrical insulation RELIANCE ELECTRIC INDUSTRIAL COMPANY (US) 1998-07-14 US disclosed
US-5770638-A CONSISTS OF TETRAHYDROFURFURYL METHACRYLATE, ONE OR MORE METHACRYLATE HAVING ATLEAST ONE DOUBLE BOND SELECTED FROM DI-2-METHACRYLOXYETHYL-2,2-4-TRIMETHYLHEXAMETHYLENE DICARBAMATE AND OTHER ACRYLATED CARBAMATE AND PHOTOINITIATORS GC CORPORATION (JP) 1998-06-23 US disclosed
US-5707236-A ABSORBS RESIN MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-13 US disclosed
US-5670258-A CONSISTS OF ION-CONTAINING, SILOXY CONTAINING COATING; DENTAL CEMENT WITH IMPROVED STRENGTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-23 US disclosed
EP-0694298-A1 PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME SHOFU INC. (JP) 1996-01-31 EP disclosed
EP-0036272-B1 PERMANENT DENTAL RESTORATIVE COMPOSITIONS AND METHODS OF USING THEM ROHM AND HAAS COMPANY (US) 1985-01-09 EP disclosed