Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.92 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.92 |
| ▸ | TSHR | P16473 | 6/20 | 0.92 |
| ▸ | HPGD | P15428 | 4/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.92 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.92 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.92 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.92 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrene SCHEMBL1284786 | 1.00 | ALDH1A1 (0.92) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL2317731 | 0.96 | ALDH1A1 (0.85) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL29429699 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL223412 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL1650929 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL1332849 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL9130 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL4578338 | 0.93 | ALDH1A1 (0.79) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL23319293 | 0.92 | ALDH1A1 (0.92) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Pyrene SCHEMBL4977930 | 0.92 | ALDH1A1 (0.92) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744093-B2 | Organic light-emitting diode, organic light-emitting display including the same, and method of manufacturing the same | LG DISPLAY CO., LTD. (KR) | 2023-08-29 | — | — | US | claimed |
| CN-112679377-B | Preparation method of N-acylpyrene amine and preparation method of 1-hydroxypyrene | 江苏广域化学有限公司 | 2022-09-20 | — | — | CN | claimed |
| US-20220255032-A1 | ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING DISPLAY INCLUDING THE SAME, AND METHOD OF MANUFACTURING THE SAME | LG DISPLAY CO., LTD. (KR) | 2022-08-11 | — | — | US | claimed |
| US-11322704-B2 | Organic light-emitting diode, organic light-emitting display including the same, and method of manufacturing the same | LG DISPLAY CO., LTD. (KR) | 2022-05-03 | — | — | US | claimed |
| US-11296295-B2 | Organic light-emitting diode, organic light-emitting display including the same, and method of manufacturing the same | LG DISPLAY CO., LTD. (KR) | 2022-04-05 | — | — | US | claimed |
| CN-109776335-B | Amine derivative of pyrene, preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-20210143353-A1 | ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING DISPLAY INCLUDING THE SAME, AND METHOD OF MANUFACTURING THE SAME | LG DISPLAY CO., LTD. (KR) | 2021-05-13 | — | — | US | claimed |
| CN-112679377-A | Preparation method of N-acylpyrene amine and preparation method of 1-hydroxypyrene | 江苏广域化学有限公司 | 2021-04-20 | — | — | CN | claimed |
| US-10862057-B2 | Organic light-emitting diode, organic light-emitting display including the same, and method of manufacturing the same | LG DISPLAY CO., LTD. (KR) | 2020-12-08 | — | — | US | claimed |
| US-20200203650-A1 | ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING DISPLAY INCLUDING THE SAME, AND METHOD OF MANUFACTURING THE SAME | LG DISPLAY CO., LTD. (KR) | 2020-06-25 | — | — | US | claimed |
| CN-1725538-A | The manufacture method of membrane electrode assembly, fuel battery, fuel cell system and membrane electrode assembly | SANYO ELECTRIC CO (JP) | 2006-01-25 | — | — | CN | claimed |
| EP-1608650-A1 | PYRENE-LINKED PYRROLO(2,1-C)(1,4)BENZODIAZEPINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Council of Scientific and Industrial Research (IN) | 2005-12-28 | — | — | EP | claimed |
| US-20050245836-A1 | detectors comprising nanostructure tubes, wires, fibers or rods disposed over substrates, having electrodes and recognition material configured to interact with carbon dioxide | NANOMIX, INC. | 2005-11-03 | — | — | US | claimed |
| WO-2005062031-A1 | NANOELECTRONIC CAPNOMETER ADAPTER | NANOMIX, INC. (US) | 2005-07-07 | — | — | WO | claimed |
| US-20050129573-A1 | Carbon dioxide nanoelectronic sensor | NANOMIX, INC. | 2005-06-16 | — | — | US | claimed |
| CN-1610984-A | Method for preparing plasma polymerized polymer electrolyte film and plasma polymerization coated polypyrrole film | MUELLER JOERG (DE) | 2005-04-27 | — | — | CN | claimed |
| WO-2005026694-A2 | CARBON DIOXIDE NANOELECTRONIC SENSOR | NANOMIX, INC. (US) | 2005-03-24 | — | — | WO | claimed |
| WO-2004087711-A1 | PYRENE-LINKED PYRROLO (2,1-C) (1,4) BENZODIAZEPINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | COUNCIL OF SCENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | claimed |
| US-6800622-B1 | DNA BINDING, ANTITUMOUR ACTIVITY | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-05 | — | — | US | claimed |
| US-20040192677-A1 | PYRENE-LINKED PYRROLO[2,1--C][1,4]BENZODIAZEPINE HYBRIDS USEFUL AS ANTI-CANCER AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192677-A1 | PYRENE-LINKED PYRROLO[2,1--C][1,4]BENZODIAZEPINE HYBRIDS USEFUL AS ANTI-CANCER AGENTS | TOP2B, TOP1, PBRM1 | ALDH1A1 1156/4885HSD17B10 3589/4885TSHR 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.