SCHEMBL32673087

SCHEMBL32673087

COc1cccc(C[C@@H](c2c[nH]cn2)c2cccc3c2CCO3)n1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.32
EED O75530 1/20 0.31
SUZ12 Q15022 1/20 0.31
EZH2 Q15910 1/20 0.31
KDM1A O60341 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
SLC9A1 P19634 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32673031 1.00 P2RX7 (0.32) P2RX7EEDSUZ12EZH2KDM1A
SCHEMBL32672783 0.84 SLC6A2 (0.31) KDM1AMAOAMAOB
SCHEMBL32672759 0.84 SLC6A2 (0.31) KDM1AMAOAMAOB
SCHEMBL32673121 0.83 GRIN2D (0.33) SLC9A1
SCHEMBL32673039 0.83 GRIN2D (0.33) SLC9A1
SCHEMBL32672962 0.82 KDM1A (0.33) KDM1AMAOAMAOB
SCHEMBL32673185 0.82 KDM1A (0.33) KDM1AMAOAMAOB
SCHEMBL32673041 0.81 CYP1A2 (0.33) EEDSUZ12EZH2SLC9A1
SCHEMBL32672852 0.79 CTSA (0.35) KDM1AMAOAMAOB
SCHEMBL32673189 0.79 CTSA (0.35) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042769-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS ALCEPTOR THERAPEUTICS INC (US) 2026-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042769-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS ADRB2, ADRB1, ADRB3 P2RX7 321/4885EED 4403/4885SUZ12 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.