SCHEMBL32673121

SCHEMBL32673121

c1ccc(C[C@H](c2c[nH]cn2)c2cccc3c2CCO3)nc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
SLC6A4 P31645 1/20 0.33
PTPRA P18433 1/20 0.33
SLC9A1 P19634 1/20 0.31
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32673039 1.00 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL32673041 0.87 CYP1A2 (0.33) SLC9A1
SCHEMBL32673108 0.83 SLC6A4 (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL32673063 0.83 SLC6A4 (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL32673031 0.83 P2RX7 (0.32) SLC9A1
SCHEMBL32673087 0.83 P2RX7 (0.32) SLC9A1
SCHEMBL32673081 0.81 EED (0.34) SLC9A1FDPS
SCHEMBL32673012 0.80 SLC6A4 (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL32673008 0.80 SLC6A4 (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL32672927 0.76 GRIN2D (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042769-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS ALCEPTOR THERAPEUTICS INC (US) 2026-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042769-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS ADRB2, ADRB1, ADRB3 GRIN2D 672/4885GRIN3B 501/4885GRIN1 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.