Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18346711 | 1.00 | ALOX15 (0.42) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL20348810 | 0.90 | LMNA (0.39) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL20348812 | 0.90 | MAPK1 (0.38) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL32674333 | 0.90 | MAPK1 (0.38) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL5104127 | 0.90 | MAPK1 (0.38) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL12868635 | 0.83 | ALDH1A1 (0.41) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL32674026 | 0.83 | ALDH1A1 (0.41) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL17479967 | 0.83 | ALDH1A1 (0.41) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL26529108 | 0.83 | ALDH1A1 (0.41) | ALOX15ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL26521044 | 0.83 | ALDH1A1 (0.41) | ALOX15ALDH1A1LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348344-B2 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2008-03-25 | — | — | US | disclosed |
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2007-02-01 | — | — | US | disclosed |
| US-5510509-A | CYCLIZATION DI-LOWER ALKYL MALONATE WITH 1,2-DICHLOROALKANE, POTASSIUM CARBONATE, DEHYDRATION BY AZEOTROPICAL DISTILLATION | HULS AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | CHRM1, CHRNA1, CHRNA9 | ALOX15 2054/4885ALDH1A1 680/4885LMNA 2598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.