Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634765 | 0.78 | — | — | |
| SCHEMBL17416664 | 0.77 | — | — | |
| SCHEMBL869236 | 0.77 | GOT1 (0.39) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL30176742 | 0.77 | GOT1 (0.39) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL29442588 | 0.76 | GOT1 (0.46) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL30792004 | 0.76 | GOT1 (0.46) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL1456807 | 0.76 | GOT1 (0.46) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL1964909 | 0.74 | GOT1 (0.32) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL27942235 | 0.69 | GABRA1 (0.41) | NPC1ALDH1A1TP53PKMHPGD | |
| SCHEMBL3749780 | 0.68 | KDM4E (0.48) | KDM4ENPC1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546133-B1 | N-SUBSTITUTED-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2010-03-17 | — | — | EP | claimed |