Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30176742 | 1.00 | GOT1 (0.39) | GOT1P2RX7TP53KDM4ELMNA | |
| SCHEMBL30792004 | 0.89 | GOT1 (0.46) | GOT1P2RX7TP53KDM4ELMNA | |
| SCHEMBL1456807 | 0.89 | GOT1 (0.46) | GOT1P2RX7TP53KDM4ELMNA | |
| SCHEMBL29442588 | 0.89 | GOT1 (0.46) | GOT1P2RX7TP53KDM4ELMNA | |
| SCHEMBL3749780 | 0.79 | KDM4E (0.48) | GOT1P2RX7TP53KDM4ELMNA | |
| SCHEMBL13911004 | 0.78 | GOT1 (0.42) | GOT1P2RX7TP53KDM4ELMNA | |
| SCHEMBL29696261 | 0.77 | KDM4E (0.52) | GOT1TP53KDM4ELMNAALDH1A1 | |
| SCHEMBL1993381 | 0.77 | KDM4E (0.52) | GOT1TP53KDM4ELMNAALDH1A1 | |
| SCHEMBL3267436 | 0.77 | KDM4E (0.33) | GOT1TP53KDM4ELMNAALDH1A1 | |
| SCHEMBL322178 | 0.75 | KDM4E (0.70) | TP53KDM4ELMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367144-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | REMICINE IP B V (NL) | 2025-12-04 | — | — | US | claimed |
| US-12419848-B2 | Treatment of hyperinflammatory syndrome | Remicine IP B.V. (NL) | 2025-09-23 | — | — | US | claimed |
| CN-112538082-B | Pyrazolooxo diaza compounds as BTK inhibitors | 鲁南制药集团股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| US-20230128348-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Remicine IP B.V. (NL) | 2023-04-27 | — | — | US | claimed |
| EP-4125843-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Nomoreitis B.V. (BE) | 2023-02-08 | — | — | EP | claimed |
| CN-114605367-A | Linker containing coumarin and antibody conjugate drug containing same | 中国人民解放军军事科学院军事医学研究院 | 2022-06-10 | — | — | CN | claimed |
| WO-2021201680-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | HASAN DJOHAN (BE) | 2021-10-07 | — | — | WO | claimed |
| WO-2010074480-A2 | NOVEL PYRAZOLODIAZEPINE COMPOUNDS AS A TRANSGLUTAMINASE INHIBITOR, THE PREPARATION METHOD THEREOF AND A COMPOSITION CONTAINING THE SAME | NATIONAL CANCER CENTER (KR) | 2010-07-01 | — | — | WO | claimed |
| US-20250367144-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | REMICINE IP B V (NL) | 2025-12-04 | — | — | US | disclosed |
| US-12419848-B2 | Treatment of hyperinflammatory syndrome | Remicine IP B.V. (NL) | 2025-09-23 | — | — | US | disclosed |
| EP-4582147-A2 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Remicine IP B.V. (NL) | 2025-07-09 | — | — | EP | disclosed |
| EP-4125843-B1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | REMICINE IP B V (NL) | 2025-05-21 | — | — | EP | disclosed |
| CN-113135918-B | Pyrazolo [1,2] diaza compounds | 鲁南制药集团股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20230128348-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Remicine IP B.V. (NL) | 2023-04-27 | — | — | US | disclosed |
| US-5723602-A | ANGIOTENSIN CONVERTING ENZYME AND ENDOPEPTIDASE INHIBITORS, CARDIOVASCULAR DISORDERS | E. R. SQUIBB & SONS, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5580979-A | Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions | TRUSTEES OF TUFTS UNIVERSITY (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1995025118-A2 | INHIBITORS OF SH2 DOMAIN INTERACTIONS | TRUSTEES OF TUFTS UNIVERSITY (US) | 1995-09-21 | — | — | WO | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |