SCHEMBL3267502

SCHEMBL3267502

CC=Cc1c(C)cc(C)c(C)c1C=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267495 1.00 CYP3A4 (0.31) CYP3A4MAPT
SCHEMBL1311847 0.79 CYP3A4 (0.38) CYP3A4MAPT
SCHEMBL3267611 0.77 CYP3A4 (0.32) CYP3A4MAPT
SCHEMBL20012058 0.76 ALDH1A1 (0.33) CYP3A4
SCHEMBL1313257 0.75 CYP3A4 (0.35) CYP3A4MAPT
SCHEMBL6551606 0.74 CYP3A4 (0.38) CYP3A4MAPT
SCHEMBL547850 0.71 ALDH1A1 (0.39) CYP3A4MAPT
SCHEMBL3271920 0.70 CYP1A2 (0.35) CYP3A4MAPT
SCHEMBL204976 0.70 CYP3A4 (0.44) CYP3A4MAPT
SCHEMBL22508507 0.68 TUBB1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1914229-B1 NOVEL CERCOSPORAMIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2010-06-16 EP disclosed
US-20090036492-A1 Novel Cercosporamide Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-02-05 US disclosed
EP-1914229-A1 NOVEL CERCOSPORAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036492-A1 Novel Cercosporamide Derivative GPR119, CBR3, SLC5A2 CYP3A4 1027/4885MAPT 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.