Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP5 | P51878 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3274799 | 0.88 | FAAH (0.53) | FAAHADRB1FEN1KDM4EALDH1A1 | |
| SCHEMBL13309353 | 0.84 | ADRB1 (0.52) | FAAHADRB1FEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3273474 | 0.83 | KDM4E (0.51) | FAAHADRB1FEN1KDM4EALDH1A1 | |
| SCHEMBL3274902 | 0.80 | FAAH (0.53) | FAAHKMOFEN1 | |
| Hydrochloric Acid SCHEMBL3275509 | 0.80 | ADRB1 (0.54) | ADRB1KDM4EALDH1A1ROCK2ACHE | |
| SCHEMBL12469782 | 0.79 | FAAH (0.54) | FAAHADRB1KDM4EALDH1A1CCNT1 | |
| Hydrochloric Acid SCHEMBL3270373 | 0.78 | ADRB1 (0.52) | FAAHADRB1KDM4EALDH1A1ROCK2 | |
| Hydrochloric Acid SCHEMBL3268535 | 0.78 | FAAH (0.53) | FAAHADRB1KDM4EALDH1A1CCNT1 | |
| Hydrochloric Acid SCHEMBL3270101 | 0.78 | PIK3CA (0.51) | FAAHADRB1KMOKDM4EALDH1A1 | |
| SCHEMBL3272680 | 0.77 | FAAH (0.53) | FAAHADRB1FEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2199282-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090163508-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | FAAH 1/4885ADRB1 594/4885KMO 1059/4885 |
| US-20090163508-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | FAAH 1/4885ADRB1 594/4885KMO 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.