SCHEMBL32676351

SCHEMBL32676351

O=C(COc1ccccc1)N1CCCc2cccnc21

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
KMT2A Q03164 5/20 0.54
MEN1 O00255 4/20 0.54
ALDH1A1 P00352 2/20 0.54
GAA P10253 2/20 0.52
TSHR P16473 2/20 0.52
KDM4E B2RXH2 1/20 0.50
TP53 P04637 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362288 0.80 HDAC1 (0.48) MAPTSMN1; SMN2KMT2AMEN1GAA
SCHEMBL6013073 0.80 HDAC1 (0.48) MAPTSMN1; SMN2KMT2AMEN1GAA
SCHEMBL28604201 0.76 AVPR2 (0.48) MAPTSMN1; SMN2KMT2AMEN1GAA
SCHEMBL16671108 0.76 CYP11B2 (0.61)
SCHEMBL29489948 0.76 CYP11B2 (0.61)
Hydrochloric Acid SCHEMBL30640657 0.74 CYP11B2 (0.60)
SCHEMBL18997597 0.74 CPT1A (0.46) MAPTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL29219465 0.73 FGFR4 (0.70) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL3404241 0.73 RAB9A (1.00) MAPTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL861264 0.72 POLB (0.45) MAPTGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048130-A1 ALPHA-V BETA-6 (avb6) INTEGRIN LIGANDS FOR EXTRAHEPATIC DELIVERY ALNYLAM PHARMACEUTICALS INC (US) 2026-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048130-A1 ALPHA-V BETA-6 (avb6) INTEGRIN LIGANDS FOR EXTRAHEPATIC DELIVERY ITGB6, ITGA6, ITGA2B MAPT 4795/4885NPC1 3287/4885RAB9A 1090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.