SCHEMBL3267905

SCHEMBL3267905

O=C(O)c1ccc(N=Nc2ccccc2)c(C(=O)O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.71
MEN1 O00255 4/20 0.71
KMT2A Q03164 4/20 0.71
TRPA1 O75762 1/20 0.61
IDE P14735 1/20 0.54
KDM4E B2RXH2 1/20 0.50
MYC P01106 1/20 0.49
PTPN1 P18031 2/20 0.47
PTPN6 P29350 1/20 0.47
PTPN11 Q06124 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.45
RAB9A P51151 2/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
GAA P10253 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
CDC25A P30304 1/20 0.43
CDC25B P30305 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28968873 0.86 TRPA1 (0.61) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL988011 0.83 MEN1 (1.00) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL522909 0.83 MEN1 (1.00) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL6740933 0.83 TRPA1 (0.61) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL4650520 0.83 TRPA1 (0.61) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL29032673 0.81 TDP1 (0.60) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL6692609 0.81 TDP1 (0.60) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL28907337 0.81 IDE (0.75) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL30827268 0.81 IDE (0.75) MAPTMEN1KMT2ATRPA1IDE
SCHEMBL169230 0.80 IDE (0.79) MAPTMEN1KMT2ATRPA1IDE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2855490-A1 IMPROVED ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE Centre National de la Recherche Scientifique (CNRS) (FR) 2015-04-08 EP claimed
WO-2013178954-A1 IMPROVED ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2013-12-05 WO claimed
EP-2193136-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE Centre National De La Recherche Scientifique-CNRS (FR) 2010-06-09 EP claimed
WO-2009077671-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2009-06-25 WO claimed
EP-2855490-A1 IMPROVED ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE Centre National de la Recherche Scientifique (CNRS) (FR) 2015-04-08 EP disclosed
WO-2013178954-A1 IMPROVED ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2013-12-05 WO disclosed
EP-2193137-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES Centre National De La Recherche Scientifique-CNRS (FR) 2010-06-09 EP disclosed
WO-2009077670-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2009-06-25 WO disclosed