SCHEMBL4650520

SCHEMBL4650520

O=C(O)c1ccc(N=Nc2ccccc2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.61
MAPT P10636 7/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
L3MBTL1 Q9Y468 4/20 0.50
POLB P06746 2/20 0.50
GAA P10253 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
PTGS2 P35354 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
GLO1 Q04760 2/20 0.49
RPS6KA3 P51812 1/20 0.49
EGFR P00533 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740933 1.00 TRPA1 (0.61) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL29465675 0.91 TRPA1 (0.58) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL9987224 0.89 CA12 (0.61) TRPA1MAPTL3MBTL1POLBGAA
SCHEMBL12620637 0.83 HDAC6 (0.47) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL1803799 0.83 HDAC6 (0.47) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL3267905 0.83 MAPT (0.71) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL1811198 0.82 RAB9A (0.60) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL1811197 0.82 RAB9A (0.60) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL29032673 0.81 TDP1 (0.60) TRPA1MAPTMEN1KMT2AL3MBTL1
SCHEMBL6692609 0.81 TDP1 (0.60) TRPA1MAPTMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130115230-A1 DELIVERY PROTEINS AUGMENTA BIOLOGICALS, LLC (US) 2013-05-09 US disclosed
EP-2563396-A2 DELIVERY PROTEINS Augmenta Biologicals LLC (US) 2013-03-06 EP disclosed
WO-2012158195-A2 TOXIN AND PATHOGEN CLEARANCE AUGMENTA BIOLOGICALS, LLC (US) 2012-11-22 WO disclosed
EP-1386160-B1 METHOD FOR DETECTING BLOOD CELL ANTIGENS AND THE ANTIBODIES IN RESPONSE TO THE SAME KIESEWETTER HOLGER (DE) 2008-09-17 EP disclosed
US-20040142492-A1 Method for detecting blood cell antigens and the antibodies in response to the same KIESEWETTER HOLGER (DE) 2004-07-22 US disclosed
EP-1386160-A2 METHOD FOR DETECTING BLOOD CELL ANTIGENS AND THE ANTIBODIES IN RESPONSE TO THE SAME Kiesewetter, Holger (DE) 2004-02-04 EP disclosed
WO-2002090989-A2 METHOD FOR DETECTING BLOOD CELL ANTIGENS AND THE ANTIBODIES IN RESPONSE TO THE SAME KIESEWETTER HOLGER (DE) 2002-11-14 WO disclosed