SCHEMBL522909

SCHEMBL522909

O=C(O)c1cc(O)ccc1N=Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 1.00
KMT2A Q03164 7/20 1.00
MAPT P10636 4/20 1.00
IDE P14735 1/20 0.68
NPC1 O15118 2/20 0.52
MYC P01106 1/20 0.49
EGFR P00533 1/20 0.49
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
ALOX5 P09917 1/20 0.48
PTGS2 P35354 1/20 0.48
TRPA1 O75762 1/20 0.47
GAA P10253 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
PDE4A P27815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988011 1.00 MEN1 (1.00) MEN1KMT2AMAPTIDENPC1
SCHEMBL4727984 0.89 MEN1 (0.79) MEN1KMT2AMAPTIDEMYC
SCHEMBL8726508 0.86 MEN1 (0.76) MEN1KMT2AMAPTIDENPC1
SCHEMBL28606354 0.85 MEN1 (0.74) MEN1KMT2AMAPTIDENPC1
SCHEMBL623529 0.83 MEN1 (0.70) MEN1KMT2AMAPTIDENPC1
SCHEMBL3267905 0.83 MAPT (0.71) MEN1KMT2AMAPTIDENPC1
SCHEMBL453284 0.81 IDE (1.00) MEN1KMT2AMAPTIDENPC1
SCHEMBL453285 0.81 IDE (1.00) MEN1KMT2AMAPTIDENPC1
SCHEMBL29401042 0.81 IDE (1.00) MEN1KMT2AMAPTIDENPC1
SCHEMBL12100493 0.81 IDE (1.00) MEN1KMT2AMAPTIDENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12466894-B2 Anti-MUC16 antibodies and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-11-11 US claimed
CN-119874560-A Rare earth-polyacid-based compound and preparation method and application thereof 南通大学 2025-04-25 CN claimed
CN-119780420-A Polymer modified avidin and preparation method and application thereof 苏州大学 2025-04-08 CN claimed
CN-116333672-B UV (ultraviolet) binder suitable for camera module and preparation method thereof 广东德聚技术股份有限公司 2023-11-17 CN claimed
CN-116333672-A UV (ultraviolet) binder suitable for camera module and preparation method thereof 东莞市德聚胶接技术有限公司 2023-06-27 CN claimed
CN-111579772-B Detection reagent based on immunomagnetic bead method, preparation method thereof, kit and detection method 珠海丽珠试剂股份有限公司 2022-04-08 CN claimed
CN-111579772-A Detection reagent based on immunomagnetic bead method, preparation method thereof, kit and detection method 珠海丽珠试剂股份有限公司 2020-08-25 CN claimed
EP-1920065-B1 ANTI-ALPHA V BETA 6 ANTIBODIES AND USES THEREOF BIOGEN MA INC (US) 2018-08-29 EP claimed
CN-105051539-A Methods and reagents for the detection of biomolecules using luminescence NANOGAP SUB NM POWDER SA 2015-11-11 CN claimed
US-20150316543-A1 METHODS AND REAGENTS FOR THE DETECTION OF BIOMOLECULES USING LUMINESCENCE NANOGAP SUB NM POWDER S A (ES) 2015-11-05 US claimed
EP-2743695-A1 Methods and reagents for the detection of biomolecules using luminescence Nanogap Sub NM Powder, S.A. (ES) 2014-06-18 EP claimed
EP-2087008-A1 TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN alphaVbeta6 The Regents of the University of California (US) 2009-08-12 EP claimed
EP-1920065-A4 ANTI-ALPHA V BETA 6 ANTIBODIES AND USES THEREOF BIOGEN IDEC INC (US) 2009-07-15 EP claimed
EP-2046374-A2 COMPOSITIONS AND METHODS FOR INHIBITING GROWTH OF SMAD4-DEFICIENT CANCERS Biogen Idec MA, Inc. (US) 2009-04-15 EP claimed
WO-2008147434-A9 TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN αVβ6 UNIV CALIFORNIA (US) 2009-03-05 WO claimed
US-20080317667-A1 Compositions and methods for inhibiting growth of smad4-deficient cancers BIOGEN IDEC MA INC. (US) 2008-12-25 US claimed
WO-2008147434-A1 TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN αVβ6 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-12-04 WO claimed
EP-1920065-A2 ANTI-ALPHA V BETA 6 ANTIBODIES AND USES THEREOF Biogen Idec MA Inc. (US) 2008-05-14 EP claimed
WO-2008008315-A2 COMPOSITIONS AND METHODS FOR INHIBITING GROWTH OF SMAD4-DEFICIENT CANCERS BIOGEN IDEC MA INC. (US) 2008-01-17 WO claimed
WO-2007008712-A2 ANTI-ALPHA V BETA 6 ANTIBODIES AND USES THEREOF BIOGEN IDEC MA INC. (US) 2007-01-18 WO claimed