Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610741 | 1.00 | TSHR (0.58) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL11429558 | 0.87 | PDE7A (0.52) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL2653845 | 0.85 | CCR2 (0.55) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL5181510 | 0.83 | MAPK1 (0.60) | TSHRMAPK1CYP3A4ALDH1A1TDP1 | |
| SCHEMBL11410600 | 0.82 | AR (0.54) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL12445316 | 0.81 | MAPK1 (0.58) | TSHRMAPK1ALDH1A1TDP1LMNA | |
| SCHEMBL17347346 | 0.81 | RAB9A (0.47) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL27426321 | 0.81 | TSHR (0.46) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL11159312 | 0.80 | TDP1 (0.59) | TSHRMAPK1TDP1ARMEN1 | |
| SCHEMBL2639009 | 0.79 | SIRT6 (0.51) | TSHRMAPK1CYP3A4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4707391-A1 | NUCLEIC ACID COMPOUNDS FOR ZPI INHIBITION | e-therapeutics PLC (GB) | 2026-03-11 | — | — | EP | disclosed |