Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32682192 | 0.85 | TSHR (0.58) | CCR2MAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL3610741 | 0.85 | TSHR (0.58) | CCR2MAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL16019384 | 0.81 | MAPK1 (0.53) | CCR2MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL1562229 | 0.80 | ALDH1A1 (0.49) | CCR2MAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL4506814 | 0.79 | TDP1 (0.55) | CCR2MAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL8192824 | 0.79 | KIF11 (0.49) | CCR2MAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL1995690 | 0.79 | ALDH1A1 (0.56) | MAPK1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8147133 | 0.79 | ALDH1A1 (0.58) | MAPK1TSHRALDH1A1HPGDHIF1A | |
| SCHEMBL29398386 | 0.79 | ALDH1A1 (0.56) | MAPK1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL4618486 | 0.79 | CCR2 (0.54) | CCR2ALDH1A1TDP1VCAM1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991873-A | Low-dielectric fluorinated aromatic polyimide film and preparation method thereof | 慧创(东莞)材料技术有限责任公司 | 2023-04-21 | — | — | CN | claimed |
| CN-117304484-A | Polyimide prepolymer resin containing silicon and Cardo structure and preparation method thereof | 大连理工大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-115991873-A | Low-dielectric fluorinated aromatic polyimide film and preparation method thereof | 慧创(东莞)材料技术有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-109970602-A | A kind of synthetic method of pair of trifluoromethylbenzonitrile class compound | 北京颖泰嘉和生物科技股份有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-105712944-B | A kind of preparation method of isoxazole compounds and its intermediate | 浙江省诸暨合力化学对外贸易有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-105712912-A | Preparation method of triketone compound and triketone compound intermediate | 浙江省诸暨合力化学对外贸易有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-105646120-A | Preparation method of carboxylic acid | 浙江省诸暨合力化学对外贸易有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-101585783-B | Preparation method of o-nitrobenzonitrile series compound | BEIJING YINGTAIJIAHE TECHNOLOGY CO LTD | 2012-04-18 | — | — | CN | disclosed |
| CN-101585783-A | Preparing method of ortho-nitrobenzonitrile series compound | BEIJING YINGTAIJIAHE TECHNOLOG (CN) | 2009-11-25 | — | — | CN | disclosed |
| EP-0616807-B1 | Benzimidazole useful in the treatment of central nervous system disorders | NEUROSEARCH AS (DK) | 1998-07-08 | — | — | EP | disclosed |
| US-5554632-A | CENTRAL NERVOUS SYSTEM | NEUROSEARCH A/S (DK) | 1996-09-10 | — | — | US | disclosed |
| US-5554630-A | TREATING ANXIETY, CONVULSIONS AND SLEEP DISORDERS IN LIVING ANIMALS BY MODULATION OF THE BENZODIAZEPINE RECEPTOR OF THE CENTRAL NERVOUS SYSTEM WITH 1-/3-HETEROCYCLYLPHENYL/-BENZIMIDAZOLES | NEUROSEARCH A/S (DK) | 1996-09-10 | — | — | US | disclosed |
| EP-0616807-A1 | Benzimidazole useful in the treatment of central nervous system disorders | NEUROSEARCH A/S (DK) | 1994-09-28 | — | — | EP | disclosed |
| EP-0248746-B1 | PROCESS FOR THE PREPARATION OF 4-FLUORO-ANILINES FROM 4-HALOGEN-NITROBENZENES | RHONE-POULENC CHIMIE (FR) | 1990-04-25 | — | — | EP | disclosed |
| US-4913728-A | HERBICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0248746-A1 | Process for the preparation of 4-fluoro-anilines from 4-halogen-nitrobenzenes | RHONE-POULENC CHIMIE (FR) | 1987-12-09 | — | — | EP | disclosed |
| US-RE31831-E | Substituted phenoxybenzoic acids and esters thereof | RHONE-POULENC AGROCHIMIE (FR) | 1985-02-12 | — | — | US | disclosed |