Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268298 | 0.90 | HPGD (0.44) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL3237671 | 0.84 | HPGD (0.59) | CA12CA1CA2CA9KLKB1 | |
| SCHEMBL1725940 | 0.78 | LMNA (0.47) | HSD11B1HPGDALDH1A1MAPTKMT2A | |
| SCHEMBL3265001 | 0.76 | NAMPT (0.45) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3242896 | 0.75 | MAPT (0.54) | KLKB1KLK1HSD11B1LIPGHPGD | |
| SCHEMBL327551 | 0.74 | LMNA (0.39) | CA12CA1CA2CA9SLC6A9 | |
| SCHEMBL3241841 | 0.72 | HSD11B1 (0.59) | KLKB1KLK1HSD11B1ALDH1A1MAPT | |
| SCHEMBL3259879 | 0.72 | MAPT (0.70) | CA12CA1CA2CA9KLKB1 | |
| SCHEMBL3237674 | 0.71 | HPGD (0.59) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL1722897 | 0.71 | LMNA (0.45) | SLC6A9HSD11B1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023445-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |