Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722897 | 0.91 | LMNA (0.45) | LMNAF10SLC6A9KCNH2HSD11B1 | |
| SCHEMBL1725940 | 0.89 | LMNA (0.47) | LMNAF10HSD11B1MAPTALDH1A1 | |
| SCHEMBL3268298 | 0.83 | HPGD (0.44) | LMNANTRK1IKBKBHSD11B1MAPT | |
| SCHEMBL327168 | 0.82 | LMNA (0.48) | LMNAF10MAPTALDH1A1MEN1 | |
| SCHEMBL1723011 | 0.81 | LMNA (0.51) | LMNAF10SLC6A9KCNH2HSD11B1 | |
| SCHEMBL3242897 | 0.78 | MAPT (0.54) | NTRK1HSD11B1MAPTALDH1A1MEN1 | |
| SCHEMBL3237674 | 0.75 | HPGD (0.59) | IKBKBHSD11B1MAPTALDH1A1MEN1 | |
| SCHEMBL321271 | 0.74 | LMNA (0.45) | LMNANTRK1MAPTALDH1A1MEN1 | |
| SCHEMBL3268296 | 0.74 | CA12 (0.47) | LMNASLC6A9IKBKBHSD11B1MAPT | |
| SCHEMBL18487091 | 0.73 | LMNA (0.45) | LMNAALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500834-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | claimed |