SCHEMBL32685167

SCHEMBL32685167

Cc1ncccc1C1CC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.46
HTR1A P08908 7/20 0.43
SLC6A2 P23975 7/20 0.43
SLC6A4 P31645 7/20 0.43
SLC6A3 Q01959 3/20 0.40
CHRNB2 P17787 2/20 0.39
CHRNA4 P43681 2/20 0.39
PDK4 Q16654 1/20 0.39
HTR2C P28335 1/20 0.38
CHRNB1 P11230 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNB3 Q05901 1/20 0.37
PDK1 Q15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15354765 1.00 PDK2 (0.46) PDK2HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL27956065 0.92 HTR1A (0.41) PDK2HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL2084224 0.90 CYP11B2 (0.43) PDK2HTR1ASLC6A2SLC6A4CHRNB2
SCHEMBL27653913 0.87 HTR1A (0.58) HTR1ASLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL29353268 0.85 HTR6 (0.46) CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL27786686 0.85 HTR2C (0.59) HTR1ASLC6A2SLC6A4SLC6A3HTR2C
Hydrochloric Acid SCHEMBL15286770 0.85 HTR2C (0.59) HTR1ASLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL26971374 0.85 HTR6 (0.46) CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3
SCHEMBL29889413 0.80 HTR1A (0.49) HTR1ASLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL15286661 0.79 MEN1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK2A3, CSNK1G1 PDK2 1941/4885HTR1A 2702/4885SLC6A2 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.