Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394139 | 0.72 | ALDH1A1 (0.46) | ALDH1A1RAB9APOLBKMT2ACYP1A2 | |
| SCHEMBL10810611 | 0.70 | ALDH1A1 (0.34) | ALDH1A1RAB9APOLBKMT2ACYP1A2 | |
| SCHEMBL11904724 | 0.70 | KDR (0.41) | ALDH1A1KMT2AIGF1R | |
| SCHEMBL11307800 | 0.68 | CYP1A2 (0.57) | ALDH1A1RAB9APOLBKMT2ACYP1A2 | |
| SCHEMBL18656646 | 0.67 | ALDH1A1 (0.39) | ALDH1A1RAB9APOLBKMT2ACYP1A2 | |
| SCHEMBL13303521 | 0.67 | ALDH1A1 (0.39) | ALDH1A1RAB9APOLBKMT2ACYP1A2 | |
| SCHEMBL5401557 | 0.67 | KDM4E (0.44) | ALDH1A1RAB9APOLBKMT2ACYP1A2 | |
| SCHEMBL2491769 | 0.65 | ALDH1A1 (0.36) | ALDH1A1POLBKMT2A | |
| SCHEMBL11763540 | 0.65 | ALDH1A1 (0.32) | ALDH1A1RAB9APOLBKMT2A | |
| SCHEMBL11761527 | 0.65 | SMN1; SMN2 (0.38) | ALDH1A1RAB9APOLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029580-B1 | NOVEL INDOL-PYRROL DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DISEASES | SCHEBO BIOTECH AG (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2029580-A1 | NOVEL INDOL-PYRROL DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DISEASES | ScheBo Biotech AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007134578-A1 | NOVEL INDOL-PYRROL DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DISEASES | SCHEBO BIOTECH AG (DE) | 2007-11-29 | — | — | WO | disclosed |