Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | FLT3 | P36888 | 4/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19220179 | 0.83 | ALDH1A1 (0.43) | ALDH1A1ALKRAB9APOLBKMT2A | |
| SCHEMBL11307800 | 0.83 | CYP1A2 (0.57) | ALDH1A1RAB9APOLBKMT2AMAPT | |
| SCHEMBL7059773 | 0.82 | RAB9A (0.42) | ALDH1A1ALKRAB9AMAPTGAA | |
| SCHEMBL1079494 | 0.82 | ALDH1A1 (0.37) | ALDH1A1ALKRAB9APOLBKMT2A | |
| SCHEMBL27307246 | 0.82 | GAA (0.44) | ALDH1A1ALKRAB9AMAPTGAA | |
| SCHEMBL7717391 | 0.81 | ALDH1A1 (0.34) | ALDH1A1ALKRAB9APOLBKMT2A | |
| SCHEMBL18656646 | 0.81 | ALDH1A1 (0.39) | ALDH1A1RAB9APOLBKMT2AMAPT | |
| SCHEMBL13303521 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ALKRAB9APOLBKMT2A | |
| SCHEMBL5403308 | 0.79 | LMNA (0.45) | ALDH1A1ALKRAB9APOLBKMT2A | |
| SCHEMBL15331397 | 0.78 | ALDH1A1 (0.58) | ALDH1A1RAB9APOLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121577791-A | Gas chromatography detection method for residual quantity of 2-chloropyrrole in 5-formyl-2, 4-dimethyl-1H-pyrrole-3-carboxylic acid serving as sunitinib intermediate | 扬州市普林斯医药科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-117143083-A | Synthesis method of VEGFR inhibitor Vorolianib | 沈阳药科大学 | 2023-12-01 | — | — | CN | claimed |
| CN-112535660-B | Three-level targeted pH sensitive type nano drug-loaded micelle and preparation method and application thereof | 上海交通大学医学院附属第九人民医院 | 2022-10-25 | — | — | CN | claimed |
| CN-115124275-A | Lithium silicate-based organic-inorganic composite concrete permeation protective agent | 上海摩瑟尔科学技术有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-112535660-A | Three-level targeted pH sensitive type nano drug-loaded micelle and preparation method and application thereof | 上海交通大学医学院附属第九人民医院 | 2021-03-23 | — | — | CN | claimed |
| CN-111233841-A | Sunitinib related substance and preparation method and application thereof | 湖北扬信医药科技有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-105732583-B | A kind of target compound for treating Gliblastoma | 苏州麦迪耐斯医药科技有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-105732583-A | Targeted compound for treating glioblastoma multiforme | 苏州麦迪耐斯医药科技有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-105199715-A | Fluorescence probe based on rhodamine B derivative as well as preparation method and application thereof | UNIV HENAN POLYTECHNIC | 2015-12-30 | — | — | CN | claimed |
| US-8466190-B2 | Polymorphic forms of Sunitinib base | NATCO PHARMA LIMITED (IN) | 2013-06-18 | — | — | US | claimed |
| EP-2274303-B1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | TEVA PHARMA (IL) | 2012-08-29 | — | — | EP | claimed |
| EP-2313371-B1 | PROCESS FOR PREPARING A 3-PYRROLE SUBSTITUTED 2-INDOLINONE MALATE SALT | MEDICHEM SA (ES) | 2012-08-15 | — | — | EP | claimed |
| EP-2274303-A1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | Teva Pharmaceutical Industries Ltd. (IL) | 2011-01-19 | — | — | EP | claimed |
| US-20100160646-A1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2010-06-24 | — | — | US | claimed |
| WO-2009150523-A1 | PROCESS FOR PREPARING A 3-PYRROLE SUBSTITUTED 2-INDOLINONE MALATE SALT | MEDICHEM, S.A. (ES) | 2009-12-17 | — | — | WO | claimed |
| WO-2009128083-A1 | NOVEL POLYMORPHIC FORMS OF SUNITINIB BASE | NATCO PHARMA LIMITED (IN) | 2009-10-22 | — | — | WO | claimed |
| WO-2009124037-A1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-10-08 | — | — | WO | claimed |
| US-20090247767-A1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-10-01 | — | — | US | claimed |
| US-20260138994-A1 | FLUORESCENT DYES CONTAINING FUSED TETRACYCLIC BIS-BORON HETEROCYCLE AND USES IN SEQUENCING | ILLUMINA INC (US) | 2026-05-21 | — | — | US | disclosed |
| WO-1999061422-A1 | PYRROLE SUBSTITUTED 2-INDOLINONE PROTEIN KINASE INHIBITORS | SUGEN, INC. (US) | 1999-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138994-A1 | FLUORESCENT DYES CONTAINING FUSED TETRACYCLIC BIS-BORON HETEROCYCLE AND USES IN SEQUENCING | POLL, POLM, NSUN2 | ALDH1A1 2801/4885ALK 143/4885RAB9A 3286/4885 |
| US-20100160646-A1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | KDR, ABL1, FLT4 | ALDH1A1 1714/4885ALK 72/4885RAB9A 1117/4885 |
| US-20090247767-A1 | PROCESSES FOR PREPARING SUNITINIB AND SALTS THEREOF | KDR, ABL1, FLT4 | ALDH1A1 1714/4885ALK 72/4885RAB9A 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.