SCHEMBL32686815

SCHEMBL32686815

O=C1c2ccccc2C(Cc2ccccn2)N1Cc1ccc2[nH]c(=O)oc2c1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IL4I1 Q96RQ9 1/20 0.39
▸ SYK P43405 1/20 0.38
▸ PTDSS1 P48651 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667509 0.89 PRMT5 (0.38) IL4I1SYKPTDSS1
SCHEMBL31667193 0.89 IL4I1 (0.37) IL4I1
SCHEMBL31667131 0.89 NOS1 (0.39) IL4I1SYK
SCHEMBL31666956 0.87 PRMT5 (0.38) IL4I1
SCHEMBL31667411 0.87 NOS1 (0.39) IL4I1
SCHEMBL31667172 0.87 ALDH1A1 (0.43) IL4I1
SCHEMBL32686751 0.87 PDE3B (0.42) IL4I1
SCHEMBL31667717 0.86 MEN1 (0.45) IL4I1
SCHEMBL31666930 0.86 MEN1 (0.45) IL4I1
SCHEMBL31667679 0.86 MEN1 (0.45) IL4I1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 IL4I1 2872/4885SYK 4833/4885PTDSS1 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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