SCHEMBL32687248

SCHEMBL32687248

C#Cc1ccc(C[C@@H]2[C@H](OCC)[C@@H](OC(=O)OC(C)(C)C)CN2C(=O)OC(C)(C)C)cc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 2/20 0.33
▸ NR1H3 Q13133 2/20 0.33
▸ TACR1 P25103 4/20 0.32
▸ AR P10275 1/20 0.31
▸ DPP4 P27487 1/20 0.31
▸ GPR119 Q8TDV5 3/20 0.30
▸ KLK7 P49862 1/20 0.30
▸ GABRA1 P14867 1/20 0.30
▸ GABRG2 P18507 1/20 0.30
▸ GABRB3 P28472 1/20 0.30
▸ GABRA5 P31644 1/20 0.30
▸ GABRA2 P47869 1/20 0.30
▸ GABRA6 Q16445 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31421262 0.90 NR1H2 (0.33) NR1H2NR1H3TACR1ARDPP4
SCHEMBL31421549 0.87 NR1H2 (0.35) NR1H2NR1H3TACR1ARDPP4
SCHEMBL31421240 0.87 NR1H2 (0.32) NR1H2NR1H3TACR1ARDPP4
SCHEMBL32687063 0.84 TACR1 (0.33) NR1H2NR1H3TACR1AR
SCHEMBL32687604 0.82 CYP2D6 (0.30) —
SCHEMBL31377495 0.81 ALDH1A1 (0.37) —
SCHEMBL31421330 0.81 MCL1 (0.36) —
SCHEMBL32687199 0.81 GPR119 (0.42) NR1H2NR1H3DPP4GPR119
SCHEMBL32687357 0.79 ALDH1A1 (0.38) —
SCHEMBL31377102 0.79 CYP2D6 (0.35) NR1H2NR1H3TACR1ARGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 NR1H2 4371/4885NR1H3 4525/4885TACR1 4469/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS NR1H2 2250/4885NR1H3 2561/4885TACR1 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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