Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32687398 | 1.00 | CACNA1B (0.45) | CACNA1BALDH1A1HTTSMN1; SMN2PPIA | |
| SCHEMBL32687808 | 0.87 | PTGES (0.40) | ALDH1A1HTTSMN1; SMN2MCHR1HRH3 | |
| Hydrochloric Acid SCHEMBL32687175 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2MCHR1HRH3 | |
| Hydrochloric Acid SCHEMBL32687297 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2MCHR1HRH3 | |
| SCHEMBL19096829 | 0.76 | GPR119 (0.44) | ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL19096830 | 0.76 | GPR119 (0.44) | ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL32687673 | 0.75 | ANPEP (0.43) | CACNA1BALDH1A1SMN1; SMN2PPIALMNA | |
| SCHEMBL26388320 | 0.68 | PPIA (0.43) | CACNA1BALDH1A1HTTSMN1; SMN2PPIA | |
| SCHEMBL25629322 | 0.68 | CACNA1B (0.53) | CACNA1BALDH1A1HTTSMN1; SMN2PPARG | |
| SCHEMBL34473372 | 0.68 | CTSL (0.47) | ALDH1A1PTGESLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078134-A1 | Macrocyclic Compounds as RAS Inhibitors | BEONE MEDICINES I GMBH (CH) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078134-A1 | Macrocyclic Compounds as RAS Inhibitors | NRAS, KRAS, HRAS | CACNA1B 1137/4885ALDH1A1 2557/4885HTT 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.