SCHEMBL32687992

SCHEMBL32687992

N#CC(=Cc1cccc(-c2ccc(Cl)cc2)c1)C(N)=S

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
MAPT P10636 8/20 0.52
KDM4E B2RXH2 7/20 0.52
KMT2A Q03164 7/20 0.52
TDP1 Q9NUW8 6/20 0.52
HPGD P15428 5/20 0.52
MEN1 O00255 5/20 0.52
RECQL P46063 4/20 0.52
BLM P54132 3/20 0.52
GAA P10253 3/20 0.52
POLB P06746 3/20 0.52
MAPK1 P28482 3/20 0.52
PKM P14618 2/20 0.52
APEX1 P27695 2/20 0.52
PMP22 Q01453 2/20 0.52
RGS12 O14924 2/20 0.52
ERBB2 P04626 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688099 0.89 MAPT (0.57) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL32688074 0.86 MAPT (0.64) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL32688072 0.83 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL32687985 0.83 MAPT (0.49) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL4879813 0.81 MAPT (0.70) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL32688162 0.78 MAPT (0.66) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL19928344 0.74 MAPT (0.69) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL32688142 0.74 ALDH1A1 (0.45) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL8483397 0.74 ALDH1A1 (0.65) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL32688371 0.71 MAPT (0.56) ALDH1A1MAPTKDM4EKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK ALDH1A1 290/4885MAPT 4018/4885KDM4E 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.