SCHEMBL32688381

SCHEMBL32688381

N#Cc1c(-c2ccccc2)nc(=O)[nH]c1SCc1cccc(-c2nnn[nH]2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.49
▸ KMT2A Q03164 8/20 0.49
▸ POLB P06746 8/20 0.49
▸ ACMSD Q8TDX5 7/20 0.48
▸ TNF P01375 2/20 0.47
▸ NOD2 Q9HC29 2/20 0.47
▸ NOD1 Q9Y239 2/20 0.47
▸ PLA2G1B P04054 1/20 0.43
▸ ATG4B Q9Y4P1 1/20 0.43
▸ CTSB P07858 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ HPGD P15428 3/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ CYP2C9 P11712 2/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ PPARG P37231 2/20 0.41
▸ HTT P42858 1/20 0.41
▸ NCOA2 Q15596 1/20 0.41
▸ NCOA1 Q15788 1/20 0.41
▸ CXCR2 P25025 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20340181 0.85 KMT2A (0.42) MEN1KMT2APOLBACMSDTNF
SCHEMBL32688366 0.83 ACMSD (0.47) MEN1KMT2APOLBACMSDTNF
SCHEMBL20340099 0.82 KMT2A (0.40) MEN1KMT2APOLBACMSDTNF
SCHEMBL26404249 0.81 ALDH1A1 (0.47) MEN1KMT2APOLBACMSDALDH1A1
SCHEMBL32688120 0.81 ACMSD (0.72) MEN1KMT2APOLBACMSDTNF
SCHEMBL32688017 0.81 ACMSD (0.56) MEN1KMT2APOLBACMSDTNF
SCHEMBL32688052 0.79 MEN1 (0.56) MEN1KMT2APOLBACMSDTNF
SCHEMBL20340093 0.79 KDM4E (0.48) MEN1KMT2APOLBACMSDTNF
SCHEMBL20339819 0.78 BRD4 (0.40) MEN1KMT2APOLBACMSDTNF
SCHEMBL24087928 0.78 MEN1 (0.55) MEN1KMT2APOLBACMSDTNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK MEN1 4353/4885KMT2A 3400/4885POLB 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback