SCHEMBL32688388

SCHEMBL32688388

N#Cc1c(C(F)(F)F)nc(=O)[nH]c1SCc1nnn[nH]1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687991 0.91 — —
SCHEMBL32688253 0.88 CXCR2 (0.36) MEN1KMT2A
SCHEMBL32688285 0.81 POLB (0.40) MEN1KMT2A
SCHEMBL32688114 0.78 CXCR2 (0.41) —
SCHEMBL20339450 0.78 KDM4E (0.58) KDM4EMEN1KMT2A
SCHEMBL20339549 0.78 HSD11B1 (0.34) KDM4E
SCHEMBL20339475 0.78 HSD11B1 (0.34) KDM4E
SCHEMBL20340086 0.77 HSD11B1 (0.33) KDM4E
SCHEMBL32688268 0.77 MEN1 (0.42) MEN1KMT2A
SCHEMBL32688366 0.76 ACMSD (0.47) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK KDM4E 3207/4885MEN1 4353/4885KMT2A 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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