SCHEMBL32688253

SCHEMBL32688253

CC(C)(C)c1nc(=O)[nH]c(SCc2nnn[nH]2)c1C#N

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CXCR2 P25025 1/20 0.36
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688388 0.88 KDM4E (0.33) MEN1KMT2A
SCHEMBL32687991 0.86 — —
SCHEMBL32688114 0.78 CXCR2 (0.41) CXCR2
SCHEMBL32688366 0.76 ACMSD (0.47) CXCR2MEN1KMT2APOLB
SCHEMBL32688043 0.76 LMNA (0.45) CXCR2MEN1KMT2APOLB
SCHEMBL32688202 0.76 RAPGEF4 (0.44) CXCR2MEN1KMT2A
SCHEMBL32688407 0.76 ACMSD (0.39) CXCR2MEN1KMT2APOLB
SCHEMBL32688268 0.75 MEN1 (0.42) CXCR2MEN1KMT2APOLB
SCHEMBL32688258 0.75 HSD11B1 (0.38) CXCR2MEN1KMT2APOLB
SCHEMBL32688144 0.75 MEN1 (0.48) CXCR2MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK CXCR2 2082/4885MEN1 4353/4885KMT2A 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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