Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688259 | 0.83 | KDM4E (0.42) | CXCR2ACMSDPOLBMEN1KMT2A | |
| SCHEMBL32688041 | 0.79 | ALDH1A1 (0.41) | CXCR2ACMSDPOLBMEN1KMT2A | |
| SCHEMBL24087923 | 0.77 | ACMSD (0.53) | CXCR2ACMSDPOLBMEN1KMT2A | |
| SCHEMBL32688199 | 0.75 | HSD11B1 (0.36) | CXCR2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL32688224 | 0.73 | ALDH1A1 (0.53) | POLBKMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL23852241 | 0.72 | MEN1 (0.69) | CXCR2ACMSDPOLBMEN1KMT2A | |
| SCHEMBL32688450 | 0.72 | HSD11B1 (0.37) | HSD11B1HPGDALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL32688066 | 0.72 | RET (0.40) | HSD11B1 | |
| SCHEMBL24087918 | 0.70 | MEN1 (0.47) | CXCR2ACMSDPOLBMEN1KMT2A | |
| SCHEMBL6949420 | 0.68 | DAO (0.40) | CXCR2ACMSDPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | CXCR2 2082/4885ACMSD 142/4885POLB 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.