SCHEMBL32689461

SCHEMBL32689461

BrC1=CCCc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2A6 P11509 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
NOS3 P29474 2/20 0.36
NOS2 P35228 1/20 0.36
PDPK1 O15530 1/20 0.36
PARP1 P09874 1/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
HPGD P15428 1/20 0.35
G6PC1 P35575 1/20 0.35
TSHR P16473 1/20 0.35
ACHE P22303 1/20 0.34
SETD7 Q8WTS6 1/20 0.34
DRD4 P21917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8371987 1.00 CES1 (0.43) CES1L3MBTL1TDP1CYP2A6MAOA
SCHEMBL21822872 0.87 CYP2A6 (0.45) CES1L3MBTL1TDP1CYP2A6MAOA
SCHEMBL7960264 0.78 HTR6 (0.41) CES1L3MBTL1TDP1CYP2A6MAOA
SCHEMBL29987608 0.74 CES1 (0.40) CES1CYP2A6MAOAMAOBSIGMAR1
SCHEMBL459641 0.74 CES1 (0.40) CES1CYP2A6MAOAMAOBSIGMAR1
SCHEMBL5119030 0.74 CYP3A4 (0.42) CES1L3MBTL1TDP1HPGDTSHR
SCHEMBL2874924 0.73 CES1 (0.43) CES1L3MBTL1CYP2A6MAOAMAOB
SCHEMBL6244296 0.73 CES1 (0.43) CES1L3MBTL1CYP2A6MAOAMAOB
SCHEMBL4436441 0.73 CES1 (0.43) CES1L3MBTL1CYP2A6MAOAMAOB
SCHEMBL3630867 0.73 NOS3 (0.45) CES1L3MBTL1CYP2A6MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121717675-A Method for synthesizing compound with rotation-resistant 1, 3-diene structure through catalytic reduction coupling reaction of transition metal 兰州大学 2026-03-24 CN disclosed