Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Triclosan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HSPA5 | P11021 | 1/20 | 1.00 |
| ▸ | CBR1 | P16152 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | AGTR1 | P30556 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triclosan SCHEMBL526378 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL29354475 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL29356111 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL29367506 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL8015104 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL8975439 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL1146628 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL3895700 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL8055151 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL434693 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 86484 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122078008-A | High-strength wear-resistant composite fabric and preparation process thereof | — | 2026-05-26 | — | — | CN | claimed |
| EP-4743053-A1 | ANTIMICROBIAL SYNERGIES | Symrise AG (DE) | 2026-05-20 | — | — | EP | claimed |
| CN-117511000-B | Anti-adhesion agent and breeding colony house modifier comprising same | 成都科宏达科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2026099873-A1 | A LOW TFM CLEANSING FORMULATION AND PREPARATION THEREOF | ITC LIMITED (IN) | 2026-05-15 | — | — | WO | claimed |
| CN-122038063-A | HPV virus-resistant underwear laundry detergent based on sulfated polysaccharide compound system and preparation method thereof | 中山市妙洁精细化工有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20260131128-A1 | DISINFECTING CAP WITH PRESSURE SEAL CAPABILITY | BECTON, DICKINSON AND COMPANY (US) | 2026-05-14 | — | — | US | claimed |
| EP-4586979-B1 | WOUND CLOSURE SYSTEM HAVING MEDICANT | CILAG GMBH INT (CH) | 2026-05-13 | — | — | EP | claimed |
| CN-122011270-A | High-temperature-resistant emulsifier for FDY (fully drawn yarn) oiling agent and preparation method thereof | 浙江恒翔新材料有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122004216-A | Herbicide composition containing cyclohexene diketone lactic acid oxime ether derivative and application thereof | 郑州手性药物研究院有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-224221346-U | Production system for triclosan diazo reaction procedure | 山东奥友生物科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-4057648-A | 5-CHLORO-2-(2,4-DICHLOROPHENOXY)-PHENOL AND 2-PHENOXYETHANOL OR 2-(P-CHLOROPHENOXY)-ETHANOL | CIBA-GEIGY CORPORATION (US) | 1977-11-08 | — | — | US | claimed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| US-3989827-A | Antibacterial composition | COLGATE-PALMOLIVE COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-3982022-A | HALOGENATED O-PHENOXYPHENOLS AND PHENOXY OR PHENALKYL ALCOHOLS | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | claimed |
| US-3970576-A | 5-CHLORO-2-(2,4-DICHLOROPHENOXY)PHENOL, ETHOXYLATED ALCOHOL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-07-20 | — | — | US | claimed |
| US-3969259-A | 2,4,4'-TRICHLORO-2'-HYDROXY DIPHENYL ETHER | LEVER BROTHERS COMPANY (US) | 1976-07-13 | — | — | US | claimed |
| US-3968210-A | Synergistic germicidal compositions containing 3,5-dimethyl-4-chlorophenol | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | claimed |
| US-3959556-A | Antimicrobial blended yarns and fabrics comprised of naturally occurring fibers | MICROBAN PRODUCTS COMPANY | 1976-05-25 | — | — | US | claimed |
| US-3956510-A | NESTING, CYLINDERS, LOOPS | BEALL NELSON J | 1976-05-11 | — | — | US | claimed |
| US-3932602-A | SOLVENTS, TETRACHLORODIFLUOROETHANE | NOVITAS NUPROT SA (CH) | 1976-01-13 | — | — | US | claimed |