Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Triclosan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HSPA5 | P11021 | 1/20 | 1.00 |
| ▸ | CBR1 | P16152 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | AGTR1 | P30556 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triclosan SCHEMBL3269 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL29354475 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL29356111 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL29367506 | 1.00 | TTR (1.00) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL8015104 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL8975439 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL1146628 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL3895700 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL8055151 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR | |
| Triclosan SCHEMBL434693 | 0.98 | TTR (0.96) | TTRHPGDNR1I2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 836 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112760318-A | Reagent composition for stabilizing nucleic acid molecules and application thereof | 苏州白垩纪生物科技有限公司 | 2021-05-07 | — | — | CN | claimed |
| US-20130059320-A1 | Selective growth media for campylobacter bacteria and plating media with said growth media | RESTAINO LAWRENCE (US) | 2013-03-07 | — | — | US | claimed |
| WO-2012018888-A2 | AN ANTISEPTIC LIQUID FORMULATION, A METHOD FOR ITS USE, AND A METHOD FOR PREPARING THE FORMULATION | DERMA-GLOVE LLC (US) | 2012-02-09 | — | — | WO | claimed |
| US-20120034314-A1 | Antiseptic Liquid Formulation, A Method for Its Use, and A Method for Preparing the Formulation | DERMA-GLOVE LLC | 2012-02-09 | — | — | US | claimed |
| EP-0966248-B2 | COMPOSITIONS FOR TREATING KERATINOUS MATERIALS CONTAINING A COMBINATION OF A ZWITTERION POLYMER AND A WATER INSOLUBLE NON-VOLATILE SILICON | OREAL (FR) | 2008-04-02 | — | — | EP | claimed |
| EP-1486199-B1 | Alcoholic aerosol deodorant composition containing zinc salicylate | OREAL (FR) | 2007-10-17 | — | — | EP | claimed |
| US-6759051-B2 | HALOGENATED ALKYLNYL CARBAMATE AND A SATURATED OR UNSATURATED ACYLIC, CYCLIC POLYOL OR POLYOL ETHER FOR THE TREATMENT OF INFLAMMATORY AND/OR DESQUAMATING SKIN DISORDERS ASSOCIATED WITH MALASSEZIA SPECIES; ANTIDANDRUFF AGENT | L'OREAL (FR) | 2004-07-06 | — | — | US | claimed |
| US-20010019722-A1 | Anti-acne chrono patch | THALLIUM HOLDING COMPANY, LLC | 2001-09-06 | — | — | US | claimed |
| US-6280764-B1 | PATCH FOR THERAPY OF ACNE | LAVIPHARM LABORATORIES INC. | 2001-08-28 | — | — | US | claimed |
| US-5976565-A | Device for topical treatment of acne and its method of manufacture | LAVIPHARM LABORATORIES, INC. (US) | 1999-11-02 | — | — | US | claimed |
| EP-0836469-A4 | BACTERICIDAL COMPOSITION | PROCTER & GAMBLE (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0836469-A1 | BACTERICIDAL COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-22 | — | — | EP | claimed |
| WO-1997002010-A1 | BACTERICIDAL COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-23 | — | — | WO | claimed |
| EP-0201134-A2 | Deodorant formulation with modulating effect on perspiration | EURAND ITALIA S.p.A. (IT) | 1986-11-12 | — | — | EP | claimed |
| US-3992729-A | Carrier or support means for disposable bedpans | MILLS KENNETH WILSON | 1976-11-23 | — | — | US | claimed |
| EP-4736840-A2 | LACTOBACILLUS PLANTARUM FOR SKIN CARE | Symrise AG (DE) | 2026-05-06 | — | — | EP | disclosed |
| EP-4025675-B1 | A PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2026-03-18 | — | — | EP | disclosed |
| US-4012512-A | GROWTH-PROMOTING AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-3992729-A | Carrier or support means for disposable bedpans | MILLS KENNETH WILSON | 1976-11-23 | — | — | US | disclosed |
| US-3940430-A | AMINOALKYL | SCHWARZ SERVICES INTERNATIONAL LTD. (US) | 1976-02-24 | — | — | US | disclosed |