SCHEMBL3269280

SCHEMBL3269280

CCCCCC1CCC(c2ccc(O)c(F)c2F)CC1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
DRD1 P21728 1/20 0.36
CES2 O00748 1/20 0.35
OPRL1 P41146 5/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
CYP2C9 P11712 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7737024 1.00 MAPT (0.38) MAPTGAAMEN1KMT2ADRD1
SCHEMBL3269278 1.00 MAPT (0.38) MAPTGAAMEN1KMT2ADRD1
SCHEMBL7737027 1.00 MAPT (0.38) MAPTGAAMEN1KMT2ADRD1
SCHEMBL7737022 1.00 MAPT (0.38) MAPTGAAMEN1KMT2ADRD1
SCHEMBL20969242 0.96 MAPT (0.36) MAPTGAAMEN1KMT2ADRD1
SCHEMBL3270112 0.90 CYP2C9 (0.42) MAPTMEN1KMT2AOPRL1CYP2C9
SCHEMBL1574998 0.90 CYP2C9 (0.42) MAPTMEN1KMT2AOPRL1CYP2C9
SCHEMBL13293543 0.90 CYP2C9 (0.42) MAPTMEN1KMT2AOPRL1CYP2C9
SCHEMBL12733579 0.87 MAPT (0.38) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL18559471 0.87 MAPT (0.42) MAPTGAAMEN1KMT2AOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4349842-B1 HYDROXYAMINOPHOSPHINIC ACID DERIVATIVES MERCK PATENT GMBH (DE) 2026-05-27 EP disclosed
US-20260132157-A1 HYDROXYAMINOPHOSPHINIC ACID DERIVATIVES MERCK PATENT GMBH (DE) 2026-05-14 US disclosed
US-12424277-B2 Electronic switching device MERCK PATENT GMBH (DE) 2025-09-23 US disclosed
EP-4062453-B1 ELECTRONIC SWITCHING DEVICE MERCK PATENT GMBH (DE) 2025-06-04 EP disclosed
CN-119998303-A Hydroxy amino phosphinic acid derivatives 默克专利有限公司 2025-05-13 CN disclosed
EP-4494430-A1 ELECTRONIC SWITCHING DEVICE Merck Patent GmbH (DE) 2025-01-22 EP disclosed
US-20250011349-A1 ELECTRONIC SWITCHING DEVICE MERCK PATENT GMBH (DE) 2025-01-09 US disclosed
US-12193328-B2 Aromatic compounds and use thereof for formation of molecular layers and fabrication of switching elements for memristive devices MERCK PATENT GMBH (DE) 2025-01-07 US disclosed
CN-113812003-B Aromatic compounds 默克专利有限公司 2024-12-20 CN disclosed
CN-118923223-A Electronic switching device 默克专利有限公司 2024-11-08 CN disclosed
EP-2305627-B1 TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2014-09-17 EP disclosed
US-20140138581-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
US-8580142-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-11-12 US disclosed
US-8580142-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-11-12 US disclosed
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2011-04-21 US disclosed
US-20100328600-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2010-12-30 US disclosed
US-20100328600-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2010-12-30 US disclosed
EP-2199270-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-06-23 EP disclosed
US-7166337-B2 Liquid-crystal composition, methods of adjusting the resistance, and substituted phenols MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2007-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, LAS1L, EFHD2 MAPT 1075/4885GAA 4763/4885MEN1 2496/4885
US-20260132157-A1 HYDROXYAMINOPHOSPHINIC ACID DERIVATIVES OR10J3, OXSR1, OXER1 MAPT 3283/4885GAA 4715/4885MEN1 2409/4885
US-12193328-B2 Aromatic compounds and use thereof for formation of molecular layers and fabrication of switching elements for memristive devices CHRM1, CCNB1, CCNL2 MAPT 2663/4885GAA 2685/4885MEN1 115/4885
US-12424277-B2 Electronic switching device L1CAM, GRIN2B, NBAS MAPT 1283/4885GAA 4554/4885MEN1 1078/4885
US-20100328600-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE KIF23, MARK3, CCND3 MAPT 271/4885GAA 4848/4885MEN1 3906/4885
US-20250011349-A1 ELECTRONIC SWITCHING DEVICE L1CAM, OR10J3, GJA1 MAPT 1271/4885GAA 4561/4885MEN1 433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.