Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.78 |
| ▸ | HPGD | P15428 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.78 |
| ▸ | CA12 | O43570 | 4/20 | 0.78 |
| ▸ | CA1 | P00915 | 4/20 | 0.78 |
| ▸ | CA2 | P00918 | 4/20 | 0.78 |
| ▸ | CA9 | Q16790 | 4/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.78 |
| ▸ | CA7 | P43166 | 3/20 | 0.78 |
| ▸ | CA4 | P22748 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.78 |
| ▸ | CA6 | P23280 | 1/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL8001218 | 0.96 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL3450029 | 0.96 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL27592487 | 0.93 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL377198 | 0.93 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL11780863 | 0.93 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL4650853 | 0.91 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL7614996 | 0.91 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL28844925 | 0.89 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL10760465 | 0.89 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL8433746 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059881-A1 | Sulphur Free Composition And Lubricant Composition And Methods Thereof | THE LUBRIZOL CORPORATION (US) | 2011-03-10 | — | — | US | disclosed |
| EP-1587901-B1 | SULPHUR FREE COMPOSITION AND LUBRICANT COMPOSITION AND METHODS THEREOF | LUBRIZOL CORP (US) | 2010-06-16 | — | — | EP | disclosed |
| US-20060247140-A1 | Sulphur free composition and lubricant composition and methods thereof | LUBRIZOL CORPORATION, THE | 2006-11-02 | — | — | US | disclosed |
| EP-1587901-A2 | SULPHUR FREE COMPOSITION AND LUBRICANT COMPOSITION AND METHODS THEREOF | THE LUBRIZOL CORPORATION (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004065530-A2 | SULPHUR FREE COMPOSITION AND LUBRICANT COMPOSITION AND METHODS THEREOF | THE LUBRIZOL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |
| EP-1072623-A2 | Polyvalent metal salts of salicyclic acid resin and process for the preparation thereof | Daedong Company, Ltd. (KR) | 2001-01-31 | — | — | EP | disclosed |
| US-3905935-A | Dye laking resins for printing inks | HERCULES INC | 1975-09-16 | — | — | US | disclosed |