Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.90 |
| ▸ | HPGD | P15428 | 7/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.90 |
| ▸ | CA12 | O43570 | 1/20 | 0.90 |
| ▸ | CA1 | P00915 | 1/20 | 0.90 |
| ▸ | CA2 | P00918 | 1/20 | 0.90 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.90 |
| ▸ | CA4 | P22748 | 1/20 | 0.90 |
| ▸ | CA6 | P23280 | 1/20 | 0.90 |
| ▸ | CA7 | P43166 | 1/20 | 0.90 |
| ▸ | CA9 | Q16790 | 1/20 | 0.90 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.90 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL11780863 | 1.00 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL10760465 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29606432 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL8433746 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL17156443 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29360246 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29362663 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1509155 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1967 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL3269581 | 0.93 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308593-B2 | Additives for fuel oils | INFINEUM INTERNATIONAL LIMITED (GB) | 2019-06-04 | — | — | US | claimed |
| EP-2230226-B1 | Additives for fuel oils | INFINEUM INT LTD (GB) | 2017-01-18 | — | — | EP | claimed |
| CN-101838565-B | Additives for fuel oils | INFINEUM INT LTD | 2015-01-21 | — | — | CN | claimed |
| EP-1612256-B1 | Fuel additives comprising a colloidal metal compound. | INFINEUM INT LTD (GB) | 2012-06-13 | — | — | EP | claimed |
| CN-1715375-B | Fuel additives | INFINEUM INT LTD | 2011-04-06 | — | — | CN | claimed |
| US-20100236139-A1 | Additives for Fuel Oils | INFINEUM INTERNATIONAL LIMITED (GB) | 2010-09-23 | — | — | US | claimed |
| EP-2230226-A1 | Additives for fuel oils | Infineum International Limited (GB) | 2010-09-22 | — | — | EP | claimed |
| CN-101838565-A | Additives for fuel oils | INFINEUM INT LTD | 2010-09-22 | — | — | CN | claimed |
| CN-101760266-A | Additives for fuel oils | INFINEUM INT LTD | 2010-06-30 | — | — | CN | claimed |
| US-20100154294-A1 | Additives for Fuel Oils | TACK ROBERT D | 2010-06-24 | — | — | US | claimed |
| EP-2199377-A1 | Additives for fuel oils | Infineum International Limited (GB) | 2010-06-23 | — | — | EP | claimed |
| US-20060000140-A1 | Fuel additives | CAPROTTI RINALDO | 2006-01-05 | — | — | US | claimed |
| EP-1612256-A1 | Fuel additives comprising a colloidal metal compound. | Infineum International Limited (GB) | 2006-01-04 | — | — | EP | claimed |
| CN-1715375-A | Fuel additives | INFINEUM INT LTD (GB) | 2006-01-04 | — | — | CN | claimed |
| EP-0779883-B1 | METHOD FOR PREPARING A SUBSTITUTED 4-HYDROXYBENZALDEHYDE | RHODIA CHIMIE SA (FR) | 2000-08-16 | — | — | EP | claimed |
| US-5756853-A | MULTISTAGE REACTION OF PHENOL BY CARBOXYLATION, HYDROXYMETHYLATION, OXIDATION AND DECARBOXYLATION | RHONE-POULENC CHIMIE (FR) | 1998-05-26 | — | — | US | claimed |
| CN-1028686-C | Thermosensitive heating wire | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1995-05-31 | — | — | CN | claimed |
| CN-1070508-A | Thermosensitive heating wire | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1993-03-31 | — | — | CN | claimed |
| US-3952132-A | ALKALI METAL SALT OF A PHENOL RESIN | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-20 | — | — | US | claimed |
| CN-111176073-A | Thick film photoresist composition containing high-heat-resistance carboxyl phenolic resin | 苏州瑞红电子化学品有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-111123649-A | Negative photoresist composition containing high-heat-resistance carboxyl phenolic resin | 苏州瑞红电子化学品有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-20190256734-A1 | ADHESION PROMOTER FOR COATINGS ON METAL SURFACES | HOLLAND NOVOCHEM TECHNICAL COATINGS B.V. (NL) | 2019-08-22 | — | — | US | disclosed |
| EP-2514774-B2 | Improvements in polymers | INFINEUM INT LTD (GB) | 2019-08-14 | — | — | EP | disclosed |
| US-10344239-B2 | Additive compositions and to fuel oils | INFINEUM INTERNATIONAL LIMITED (GB) | 2019-07-09 | — | — | US | disclosed |
| US-10308593-B2 | Additives for fuel oils | INFINEUM INTERNATIONAL LIMITED (GB) | 2019-06-04 | — | — | US | disclosed |
| EP-3478776-A2 | ADHESION PROMOTER FOR COATINGS ON METAL SURFACES | Holland Novochem Technical Coatings B.V. (NL) | 2019-05-08 | — | — | EP | disclosed |
| CN-109642100-A | The adhesion promoter of coating on metal surface | 荷兰诺沃赫姆技术涂料私人有限公司 | 2019-04-16 | — | — | CN | disclosed |
| EP-3093332-B1 | IMPROVEMENTS TO ADDITIVE COMPOSITIONS AND TO FUEL OILS | INFINEUM INT LTD (GB) | 2018-03-14 | — | — | EP | disclosed |
| US-20170073600-A1 | POLYMERS | INFINEUM INT LTD (GB) | 2017-03-16 | — | — | US | disclosed |
| EP-2514803-B1 | Improvements in fuel oils | INFINEUM INT LTD (GB) | 2017-02-01 | — | — | EP | disclosed |
| EP-2230226-B1 | Additives for fuel oils | INFINEUM INT LTD (GB) | 2017-01-18 | — | — | EP | disclosed |
| CN-106147895-A | To compositions of additives and the improvement of fuel oil | 英菲诺姆国际有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20160333285-A1 | Additive Compositions and to Fuel Oils | lnfineum International Limited (GB) | 2016-11-17 | — | — | US | disclosed |
| EP-3093332-A1 | IMPROVEMENTS TO ADDITIVE COMPOSITIONS AND TO FUEL OILS | Infineum International Limited (GB) | 2016-11-16 | — | — | EP | disclosed |
| CN-102746908-B | The improvement of oil fuel | ENFENORM INTERNATIONAL CO. (GB) | 2016-04-20 | — | — | CN | disclosed |
| CN-102746447-B | The improvement of polymkeric substance | ENFENORM INTERNATIONAL CO. (GB) | 2016-03-30 | — | — | CN | disclosed |
| US-8951307-B2 | Polymers | INFINEUM INTERNATIONAL LIMITED (GB) | 2015-02-10 | — | — | US | disclosed |
| CN-101838565-B | Additives for fuel oils | INFINEUM INT LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-102120804-B | Improvements in polymers | ENFENORM INTERNATIONAL CO. (GB) | 2014-10-29 | — | — | CN | disclosed |
| US-20140144070-A1 | POLYMERS | INFINEUM INTERNATIONAL LIMITED (GB) | 2014-05-29 | — | — | US | disclosed |
| US-8710168-B2 | Polymers | INFINEUM INTERNATIONAL LIMITED (GB) | 2014-04-29 | — | — | US | disclosed |
| CN-101200659-B | Additive composition | INFINEUM INT LTD | 2013-08-28 | — | — | CN | disclosed |
| US-20120266524-A1 | FUEL OILS | INFINEUM INTERNATIONAL LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
| US-20120266528-A1 | POLYMERS | INFINEUM INTERNATIONAL LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
| EP-2514774-A1 | Improvements in polymers | Infineum International Limited (GB) | 2012-10-24 | — | — | EP | disclosed |
| EP-2514803-A1 | Improvements in fuel oils | Infineum International Limited (GB) | 2012-10-24 | — | — | EP | disclosed |
| CN-102746908-A | Improved FUEL OILS | INFINEUM INT LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-102746447-A | Improvements in polymers | INFINEUM INT LTD | 2012-10-24 | — | — | CN | disclosed |
| EP-1612256-B1 | Fuel additives comprising a colloidal metal compound. | INFINEUM INT LTD (GB) | 2012-06-13 | — | — | EP | disclosed |
| EP-2336206-B1 | Polymers and fuel oil compositions containing them | INFINEUM INT LTD (GB) | 2012-01-25 | — | — | EP | disclosed |
| CN-102120804-A | Improvements in polymers | INFINEUM INT LTD | 2011-07-13 | — | — | CN | disclosed |
| US-20110146136-A1 | Polymers | INFINEUM INTERNATIONAL LIMITED (GB) | 2011-06-23 | — | — | US | disclosed |
| EP-2336206-A1 | Polymers and fuel oil compositions containing them | Infineum International Limited (GB) | 2011-06-22 | — | — | EP | disclosed |
| CN-1715375-B | Fuel additives | INFINEUM INT LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20100236139-A1 | Additives for Fuel Oils | INFINEUM INTERNATIONAL LIMITED (GB) | 2010-09-23 | — | — | US | disclosed |
| EP-2230226-A1 | Additives for fuel oils | Infineum International Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| CN-101838565-A | Additives for fuel oils | INFINEUM INT LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-101760266-A | Additives for fuel oils | INFINEUM INT LTD | 2010-06-30 | — | — | CN | disclosed |
| US-20100154294-A1 | Additives for Fuel Oils | TACK ROBERT D | 2010-06-24 | — | — | US | disclosed |
| EP-2199377-A1 | Additives for fuel oils | Infineum International Limited (GB) | 2010-06-23 | — | — | EP | disclosed |
| US-20080141582-A1 | Additive Composition | BREAKSPEAR ANGELA PRISCILLA | 2008-06-19 | — | — | US | disclosed |
| CN-101200659-A | Additive composition | INFINEUM INT LTD (GB) | 2008-06-18 | — | — | CN | disclosed |
| CN-101172097-A | Liniment for treating bromhidrosis and confecting method thereof | DAIFU LIN (CN) | 2008-05-07 | — | — | CN | disclosed |
| US-20060059770-A1 | Fuel oils | INFINEUM INTERNATIONAL LIMITED (GB) | 2006-03-23 | — | — | US | disclosed |
| US-20060000140-A1 | Fuel additives | CAPROTTI RINALDO | 2006-01-05 | — | — | US | disclosed |
| EP-1612256-A1 | Fuel additives comprising a colloidal metal compound. | Infineum International Limited (GB) | 2006-01-04 | — | — | EP | disclosed |
| CN-1715375-A | Fuel additives | INFINEUM INT LTD (GB) | 2006-01-04 | — | — | CN | disclosed |
| US-6198377-B1 | LARGE TEMPERATURE DEPENDENCE OF IMPEDANCE AND GOOD HEAT STABILITY FOR A LONG TIME, WHERE THE PLASTIC THERMISTOR CONSISTS OF A POLYAMIDE, IODINE OR IODINE COMPOUNDS, A METAL OXIDE AND A NAPHTHYLAMINE OR HINDERED PHENOL COMPOUND | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| US-5908902-A | REACTING AN ALIPHATIC POLYOL HAVING A WEIGHT-AVERAGE MOLAR MASS M.SUB.W OF FROM 200 TO 20,000 G/MOL AND AN EPOXIDE COMPOUND HAVING AT LEAST TWO EPOXIDE GROUPS PER MOLECULE AND AN EPOXIDE GROUP CONTENT OF FROM 500 TO 10,000 MMOL/KG; RATIO | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-06-01 | — | — | US | disclosed |
| US-5756853-A | MULTISTAGE REACTION OF PHENOL BY CARBOXYLATION, HYDROXYMETHYLATION, OXIDATION AND DECARBOXYLATION | RHONE-POULENC CHIMIE (FR) | 1998-05-26 | — | — | US | disclosed |
| US-5708059-A | EPOXY RESINS, POLYHYDROXY AROMATICS, DISPERSANTS, DILUENTS AND WATER | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0782153-A1 | TEMPERATURE-SENSING POLYMER BODY AND TEMPERATURE-SENSING ELEMENT MADE THEREFROM | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| US-5616634-A | ?STYRENIZED? POLYEPOXIDES AND EPOXY RESINS; ADHESIVES; PROTECTIVE COATINGS; HARDNESS; CORROSION RESISTANCE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| US-5612394-A | EPOXY RESIN WITH DISPERSANTS AND CROSSLINKING | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5424340-A | For coating interiors of food and beverage containers | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| CN-1028686-C | Thermosensitive heating wire | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1995-05-31 | — | — | CN | disclosed |
| US-5236974-A | Stirring epoxy resin with emulsifier and solvent, then with water | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| CN-1070508-A | Thermosensitive heating wire | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1993-03-31 | — | — | CN | disclosed |
| US-4987163-A | SKIN-FREE PAINTS, MOLDING MATERIALS, ADHESIVES | HOECHST AG (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4800193-A | ANILINE, INDOLE AND PHTHALEIN DYES; COLORFASTNESS; AROMATIC SOLVENT-SOLUBLE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-01-24 | — | — | US | disclosed |
| US-4415682-A | Stable aqueous epoxide resin dispersion, a process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4337280-A | Desensitizer composition | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4172727-A | WHICH REDUCE OR EXTINGUISH CAPABILITY OF DEVELOPERS TO COLOR COLORLESS COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1979-10-30 | — | — | US | disclosed |
| US-4147830-A | Recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4078493-A | Desensitizing using dry reverse lithographic plate | FUJI PHOTO FILM CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3952132-A | ALKALI METAL SALT OF A PHENOL RESIN | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3952132-A | ALKALI METAL SALT OF A PHENOL RESIN | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308593-B2 | Additives for fuel oils | ACAD9, FASN, PCCA | ALDH1A1 409/4885KDM4E 2225/4885HPGD 975/4885 |
| US-20100236139-A1 | Additives for Fuel Oils | ACAD9, FASN, PCCA | ALDH1A1 409/4885KDM4E 2225/4885HPGD 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.