Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL321994 | 0.99 | ALDH1A1 (0.69) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1603191 | 0.99 | ALDH1A1 (0.69) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL19075841 | 0.89 | ALDH1A1 (0.84) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL20211322 | 0.89 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL15427687 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL18813443 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL17546280 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL13825148 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL6779574 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL15599417 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606885-A | Dabigatran etexilate mesylate and preparation method thereof | 安徽鼎旺医药有限公司 | 2020-09-01 | — | — | CN | claimed |
| EP-2834224-B1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN LAB LTD (IN) | 2018-06-06 | — | — | EP | claimed |
| US-20150087842-A1 | Process For The Preparation Of Benzimidazole Derivatives And Salts Thereof | MSN LABORATORIES PRIVATE LIMITED (IN) | 2015-03-26 | — | — | US | claimed |
| EP-2834224-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN Laboratories Limited (IN) | 2015-02-11 | — | — | EP | claimed |
| US-20150011589-A1 | PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND POLYMORPHS OF INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2015-01-08 | — | — | US | claimed |
| CN-104031031-A | Dabigatran etexilate preparation method | NANTONG CHANGYOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-09-10 | — | — | CN | claimed |
| CN-103694166-A | Preparation method of 3-[(3-amine-4-methylamino-benzoyl)(pyridin-2-yl)amine]ethyl propionate | SHANGHAI INST TECHNOLOGY | 2014-04-02 | — | — | CN | claimed |
| WO-2013150545-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-10-10 | — | — | WO | claimed |
| WO-2013111163-A2 | PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND POLYMORPHS OF INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2013-08-01 | — | — | WO | claimed |
| CN-110128407-B | Preparation method of dabigatran etexilate key intermediate | 连云港恒运药业有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-111606885-A | Dabigatran etexilate mesylate and preparation method thereof | 安徽鼎旺医药有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-111606885-A | Dabigatran etexilate mesylate and preparation method thereof | 安徽鼎旺医药有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-106033079-B | Method for detecting related substance imidazole in starting material F of dabigatran etexilate mesylate | 成都百裕制药股份有限公司 | 2020-08-21 | — | — | CN | disclosed |
| EP-2978750-B1 | \"SYNTHESIS OF DABIGATRAN\ | USV PRIVATE LTD (IN) | 2020-03-04 | — | — | EP | disclosed |
| US-20070185173-A1 | Process for the Preparation of the Salts of 4-(Benzimidazolylmethylamino)-Benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-09 | — | — | US | disclosed |
| US-20070185173-A1 | Process for the Preparation of the Salts of 4-(Benzimidazolylmethylamino)-Benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-09 | — | — | US | disclosed |
| WO-2007071742-A1 | IMPROVED PROCESS FOR THE PREPARATION OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES AND THE SALTS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007071742-A1 | IMPROVED PROCESS FOR THE PREPARATION OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES AND THE SALTS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007071743-A1 | IMPROVED PROCESS FOR THE PREPARATION OF THE SALTS OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007071743-A1 | IMPROVED PROCESS FOR THE PREPARATION OF THE SALTS OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185173-A1 | Process for the Preparation of the Salts of 4-(Benzimidazolylmethylamino)-Benzamides | DDC, BCKDK, IL4I1 | ALDH1A1 55/4885KMT2A 453/4885MAPK1 613/4885 |
| US-20150087842-A1 | Process For The Preparation Of Benzimidazole Derivatives And Salts Thereof | AZI2, IL4I1, ABAT | ALDH1A1 818/4885KMT2A 239/4885MAPK1 1541/4885 |
| US-20150011589-A1 | PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND POLYMORPHS OF INTERMEDIATES THEREOF | CYP1A2, CYP3A4, CYP2C9 | ALDH1A1 167/4885KMT2A 1818/4885MAPK1 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.