Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123293 | 0.77 | ALDH1A1 (0.48) | IDO1 | |
| SCHEMBL21047719 | 0.72 | KDM4C (0.42) | — | |
| SCHEMBL30986408 | 0.70 | LTA4H (0.45) | IDO1 | |
| SCHEMBL3542838 | 0.69 | KCNN3 (0.85) | HDAC6KCNN3 | |
| SCHEMBL12017975 | 0.69 | IDO1 (0.61) | IDO1 | |
| SCHEMBL7857823 | 0.68 | ALDH1A1 (0.58) | IDO1 | |
| SCHEMBL376248 | 0.68 | IDO1 (0.70) | IDO1 | |
| SCHEMBL3544239 | 0.66 | KCNN3 (0.62) | HDAC6KCNN3 | |
| SCHEMBL9251890 | 0.66 | PDE5A (0.48) | IDO1 | |
| SCHEMBL10562594 | 0.66 | IDO1 (0.45) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963311-B1 | CHROMANE SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS ACID PUMP INHIBITORS | RAQUALIA PHARMA INC (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-7723321-B2 | Chromane substituted benzimidazole derivatives | RAQUALIA PHARMA INC. (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-1963311-A1 | CHROMANE SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS ACID PUMP INHIBITORS | Pfizer, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072146-A1 | CHROMANE SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS ACID PUMP INHIBITORS | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |
| US-20070142448-A1 | Chromane Substituted Benzimidazole Derivatives | PFIZER INC. | 2007-06-21 | — | — | US | disclosed |
| WO-2007031860-A1 | INDANE SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS ACID PUMP INHIBITORS | PFIZER JAPAN INC. (JP) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142448-A1 | Chromane Substituted Benzimidazole Derivatives | HRH2, HRH4, HRH1 | HDAC6 640/4885KCNN3 481/4885IDO1 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.