Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3274660 | 0.99 | CYP1A2 (0.62) | CYP1A2CYP2C9HRH3HSD17B10ALDH1A1 | |
| SCHEMBL3269298 | 0.80 | HTR3A (0.51) | CYP1A2CYP2C9HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL3269261 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP2C9HRH3HSD17B10ALDH1A1 | |
| SCHEMBL3268563 | 0.79 | NMT1 (0.52) | PLD1CNR2ADRB1 | |
| SCHEMBL3528071 | 0.78 | CYP1A2 (0.67) | CYP1A2CYP2C9HRH3HSD17B10ALDH1A1 | |
| SCHEMBL31505927 | 0.78 | CYP1A2 (0.75) | CYP1A2CYP2C9HRH3HSD17B10ALDH1A1 | |
| SCHEMBL3529715 | 0.78 | CYP1A2 (0.66) | CYP1A2CYP2C9HRH3HSD17B10ALDH1A1 | |
| SCHEMBL26985963 | 0.78 | CYP1A2 (0.75) | CYP1A2CYP2C9HRH3HSD17B10ALDH1A1 | |
| SCHEMBL12469782 | 0.76 | FAAH (0.54) | CYP1A2CYP2C9ALDH1A1KDM4EHTR3A | |
| Hydrochloric Acid SCHEMBL3268535 | 0.75 | FAAH (0.53) | CYP1A2CYP2C9ALDH1A1KDM4EHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2199282-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090163508-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | CYP1A2 728/4885CYP2C9 805/4885HRH3 69/4885 |
| US-20090163508-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | CYP1A2 728/4885CYP2C9 805/4885HRH3 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.