Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | MME | P08473 | 7/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.41 |
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | CPA1 | P15085 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266844 | 0.88 | GHSR (0.48) | PPARGPPARAMMEACE2ACE | |
| SCHEMBL6324685 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL6319028 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL3266638 | 0.84 | MMP9 (0.51) | ALDH1A1MAPTPPARGPPARAMMP9 | |
| SCHEMBL8190605 | 0.84 | MMP9 (0.51) | ALDH1A1MAPTPPARGPPARAMMP9 | |
| SCHEMBL30688530 | 0.83 | MMP9 (0.47) | ALDH1A1MAPTMMEACEMMP9 | |
| SCHEMBL30688463 | 0.83 | MMP9 (0.48) | ALDH1A1MAPTMMEACEMMP9 | |
| SCHEMBL8171467 | 0.81 | HDAC3 (0.45) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL3361699 | 0.80 | CYP51A1 (0.46) | ALDH1A1MAPTMME | |
| SCHEMBL3267330 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTPPARGPPARASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | claimed |
| EP-1506969-B1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS US INC (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1506969-A1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| EP-1047709-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036431-A9 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2000-07-27 | — | — | WO | disclosed |
| US-6083908-A | TREATING MEDICAL DISORDERS RESULTING FROM DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2000-07-04 | — | — | US | disclosed |
| WO-1999036431-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-07-22 | — | — | WO | disclosed |