Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 10/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.45 |
| ▸ | ACE | P12821 | 8/20 | 0.45 |
| ▸ | CPA1 | P15085 | 8/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319028 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL6319021 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL8906561 | 0.88 | MME (0.40) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL7063344 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL4426088 | 0.87 | FCER2 (0.53) | MMEACE2ACECPA1MMP9 | |
| SCHEMBL4427112 | 0.87 | FCER2 (0.53) | MMEACE2ACECPA1MMP9 | |
| SCHEMBL6317992 | 0.87 | FCER2 (0.53) | MMEACE2ACECPA1MMP9 | |
| SCHEMBL8905182 | 0.87 | GHSR (0.45) | MMEACE2ACECPA1MMP9 | |
| SCHEMBL3272745 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL8171467 | 0.86 | HDAC3 (0.45) | ALDH1A1MAPTMMEACE2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939880-B2 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2005-09-06 | — | — | US | disclosed |
| US-6555570-B2 | Growth hormone secretagogous with improved bioavailability | NOVO NORDISK A/S (DE) | 2003-04-29 | — | — | US | disclosed |
| US-20030040483-A1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS (U.S.), INC. | 2003-02-27 | — | — | US | disclosed |
| US-6127391-A | A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040483-A1 | Compounds with growth hormone releasing properties | GHRHR, GHSR, GRPR | ALDH1A1 2542/4885MAPT 4357/4885MME 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.