SCHEMBL327328

SCHEMBL327328

CCCCCSS(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.43
CES2 O00748 3/20 0.40
TP53 P04637 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GMNN O75496 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
CYP2C9 P11712 1/20 0.40
BLM P54132 1/20 0.40
CA1 P00915 2/20 0.39
PPARA Q07869 2/20 0.37
EPHX1 P07099 1/20 0.36
FAAH O00519 6/20 0.36
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CES1 P23141 4/20 0.35
PLA2G6 O60733 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101877 0.98 CA2 (0.47) CA2CES2TP53HSD17B10GMNN
SCHEMBL6691473 0.98 CA2 (0.47) CA2CES2TP53HSD17B10GMNN
SCHEMBL15500216 0.98 CA2 (0.47) CA2CES2TP53HSD17B10GMNN
SCHEMBL11340050 0.95 CA2 (0.45) CA2CES2TP53HSD17B10GMNN
SCHEMBL11333558 0.95 CA2 (0.45) CA2CES2TP53HSD17B10GMNN
SCHEMBL6687367 0.95 CA2 (0.45) CA2CES2TP53HSD17B10GMNN
SCHEMBL27617655 0.95 CA2 (0.45) CA2CES2TP53HSD17B10GMNN
SCHEMBL5029419 0.92
SCHEMBL10957642 0.90 HSD17B10 (0.38) CA2CES2TP53HSD17B10GMNN
SCHEMBL1082107 0.89 TP53 (0.38) CA2CES2TP53HSD17B10GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478150-B S-deuterated methyl-aryl sulfonyl thioester compound and synthetic method and application thereof 浙江工业大学 2024-04-09 CN claimed
CN-117164488-A Method for synthesizing (E) -beta-thio vinyl sulfone compound by using organic semiconductor carbon nitride as catalyst 化学与精细化工广东省实验室 2023-12-05 CN claimed
CN-114478150-A S-deuterated methyl-aryl sulfonyl thioester compound and synthesis method and application thereof 浙江工业大学 2022-05-13 CN claimed
US-9999902-B2 Non-sticky erasable media with overcoat XEROX CORPORATION (US) 2018-06-19 US claimed
US-9507249-B2 Non-sticky erasable media with overcoat XEROX CORPORATION (US) 2016-11-29 US claimed
US-20140073602-A9 NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2014-03-13 US claimed
US-8545738-B2 Stabilized photochromic ink for reusable paper annotation XEROX CORPORATION (US) 2013-10-01 US claimed
US-20130184237-A1 NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2013-07-18 US claimed
EP-2591009-A1 NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES Fresenius Kabi Deutschland GmbH (DE) 2013-05-15 EP claimed
US-8303858-B2 Photochromic polymer with binder XEROX CORPORATION (US) 2012-11-06 US claimed
US-20080311491-A1 INKLESS REIMAGEABLE PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
EP-2003496-A1 Inkless Reimageable Printing Paper and Method Xerox Corporation (US) 2008-12-17 EP claimed
EP-2003492-A1 Inkless Reimageable Printing Paper and Method Xerox Corporation (US) 2008-12-17 EP claimed
US-7381506-B2 Reimageable paper XEROX CORPORATION (US) 2008-06-03 US claimed
US-7316875-B2 Photochromic paper with improved bistability XEROX CORPORATION (US) 2008-01-08 US claimed
US-7229740-B2 Reimageable paper XEROX CORPORATION (US) 2007-06-12 US claimed
US-20070072110-A1 Substrate coated with a mixture of a solvent and an imaging layer containing a photochromic material exhibiting a reversible homogeneous-heterogeneous transition between a dispersed colorless state and a colored state that separates out of the solvent in the form of opaque, polydisperse crystals. XEROX CORPORATION (US) 2007-03-29 US claimed
US-20070054215-A1 Substrate coated with a polymer binder and an imaging layer containing a photochromic material exhibiting a reversible homogeneous-heterogeneous transition between a dispersed colorless state and a colored state that separates out of the binder in the form of opaque, polydisperse crystals. XEROX CORPORATION (US) 2007-03-08 US claimed
US-20060251988-A1 Photochromic paper with improved bistability XEROX CORPORATION (US) 2006-11-09 US claimed
US-4009087-A N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE M&T CHEMICALS INC. (US) 1977-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130184237-A1 NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES NOS2, NOS3, NOS1 CA2 2768/4885CES2 169/4885TP53 3857/4885
US-20140073602-A9 NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES NOS2, NOS3, NOS1 CA2 2768/4885CES2 169/4885TP53 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.