⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526468 | 0.82 | — | — | |
| SCHEMBL27510365 | 0.74 | — | — | |
| SCHEMBL8698383 | 0.74 | PARP1 (0.41) | — | |
| SCHEMBL13506146 | 0.73 | RAB9A (0.54) | — | |
| SCHEMBL3273322 | 0.73 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL4352197 | 0.73 | — | — | |
| SCHEMBL114011 | 0.73 | — | — | |
| SCHEMBL27831516 | 0.73 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL29663370 | 0.71 | SMYD3 (0.40) | — | |
| SCHEMBL151256 | 0.71 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3999183-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | Ono Pharmaceutical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |
| CN-111253317-A | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111187218-A | Application of 1-substituted-1H-imidazole-2-carboxylic acid compounds in preparation of metal β -lactamase inhibitor | 四川大学 | 2020-05-22 | — | — | CN | disclosed |
| CN-104877001-A | Antifungal Agents | SCYNEXIS INC | 2015-09-02 | — | — | CN | disclosed |
| CN-102176827-B | Antifungal formulations | SCYNEXIS INC | 2015-05-20 | — | — | CN | disclosed |
| CN-103930422-A | Heterocyclic compounds and their use | INFINITY PHARMACEUTICALS INC | 2014-07-16 | — | — | CN | disclosed |
| US-20120071628-A1 | TOPICAL THERAPEUTIC AGENT FOR OPHTHALMIC DISEASES COMPRISING COMPOUND CAPABLE OF BINDING SPECIFICALLY TO DNA SEQUENCE | NIHON UNIVERSITY (JP) | 2012-03-22 | — | — | US | disclosed |
| CN-102190794-A | Method for synthesizing rigid chain polyamide and synthetic product thereof | JUNMA TYRE CORD CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-102176827-A | Antifungal formulations | MERCK SHARP & DOHME | 2011-09-07 | — | — | CN | disclosed |
| US-20110046070-A1 | GENE EXPRESSION INHIBITOR SELECTIVE FOR MATRIX METALLOPROTEINASE-9 GENE | NIHON UNIVERSITY (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2266583-A1 | GENE EXPRESSION INHIBITOR SELECTIVE FOR MATRIX METALLOPROTEINASE-9 GENE | Nihon University (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7807844-B2 | TGF-β gene expression inhibitor | NIHON UNIVERSITY (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20080103187-A1 | Tgf-Beta Gene Expression Inhibitor | GENTIER BIOSYSTEMS, INC. (JP) | 2008-05-01 | — | — | US | disclosed |